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公开(公告)号：US06653287B1
公开(公告)日：2003-11-25
申请号：US09660590
申请日：2000-09-13
IPC分类号： A61K3817
CPC分类号： C07K16/244 , A61K38/12 , A61K39/3955 , A61K2300/00
摘要： A leukemia inhibitory factor antagonist, alone or in combination with an endothelin antagonist, may be used for treatment of heart failure. The antagonist(s) are administered in a chronic fashion, in therapeutically effective amounts, to achieve this purpose.
摘要翻译： 单独或与内皮素拮抗剂组合的白血病抑制因子拮抗剂可用于治疗心力衰竭。 拮抗剂以治疗有效量以慢性方式施用以达到该目的。
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2.发明授权Method of treating heart failure using leukemia inhibitory factor antagonists optionally with endothelin antagonists 失效使用白细胞抑制因子拮抗剂任选地用内皮素拮抗剂治疗心力衰竭的方法
公开(公告)号：US5837241A
公开(公告)日：1998-11-17
申请号：US693826
申请日：1996-07-26
IPC分类号： A61K38/00 , A61K38/17 , A61K38/20 , A61K39/395 , C07K16/24 , C07K16/18 , C07K16/22 , C12N5/12
CPC分类号： C07K16/244 , A61K38/12 , A61K39/3955
摘要： A leukemia inhibitory factor antagonist, alone or in combination with an endothelin antagonist, may be used for treatment of heart failure. The antagonist(s) are administered in a chronic fashion, in therapeutically effective amounts, to achieve this purpose.
摘要翻译： 单独或与内皮素拮抗剂联合的白血病抑制因子拮抗剂可用于治疗心力衰竭。 拮抗剂以治疗有效量以慢性方式施用以达到该目的。
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公开(公告)号：US6156733A
公开(公告)日：2000-12-05
申请号：US23967
申请日：1998-02-13
IPC分类号： A61K38/00 , A61K38/17 , A61K38/20 , A61K39/395 , C07K16/24 , C07K14/47 , C07K14/705 , C07K14/715
CPC分类号： C07K16/244 , A61K38/12 , A61K39/3955
摘要： A leukemia inhibitory factor antagonist, alone or in combination with an endothelin antagonist, may be used for treatment of heart failure. The antagonist(s) are administered in a chronic fashion, in therapeutically effective amounts, to achieve this purpose.
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4.发明授权Use of leukemia inhibitory factor specific antibodies and endothelin antagonists for treatment of cardiac hypertrophy 失效使用白血病抑制因子特异性抗体和内皮素拮抗剂治疗心脏肥大
公开(公告)号：US5573762A
公开(公告)日：1996-11-12
申请号：US428002
申请日：1995-04-24
CPC分类号： C07K16/244 , A61K38/12 , A61K39/3955
摘要： A leukemia inhibitory factor antagonist, alone or in combination with an endothelin antagonist, may be used for treatment of heart failure. The antagonist(s) are administered in a chronic fashion, in therapeutically effective amounts, to achieve this purpose.
摘要翻译： 单独或与内皮素拮抗剂组合的白血病抑制因子拮抗剂可用于治疗心力衰竭。 拮抗剂以治疗有效量以慢性方式施用以达到该目的。
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