公开(公告)号：US20230160914A1

公开(公告)日：2023-05-25

申请号：US17766118

申请日：2020-10-02

Applicant: The University of Tokyo ,  NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT

Inventor： Takahisa Murata ,  Tatsuro Nakamura ,  Yuta Hamasaki ,  Yukihiro Ohya ,  Yusuke Inuzuka ,  Kiwako Yamamoto

IPC: G01N33/92 ,  C12Q1/6883

CPC classification number: G01N33/92 ,  C12Q1/6883 ,  C12Q2600/158 ,  C12Q1/6851

Abstract: An object of the present disclosure is to provide a novel method for detecting atopic dermatitis and a novel method for determining a therapeutic effect on atopic dermatitis. The present disclosure provides a method for detecting atopic dermatitis, including the step of measuring the concentration of a lipid metabolite in a biological sample of a subject. The present disclosure also provides a method for determining a therapeutic effect on atopic dermatitis, including the step of measuring the concentration of a lipid metabolite in a biological sample of a subject.

公开(公告)号：US11185561B2

公开(公告)日：2021-11-30

申请号：US15881302

申请日：2018-01-26

Applicant: National Center for Child Health and Development

Inventor： Yukihiro Ohya ,  Shigenori Kabashima ,  Osamu Natsume ,  Hirohisa Saito

IPC: A61K35/57 ,  A61P43/00 ,  A61K9/00 ,  A61K38/17

Abstract: The present invention provides an egg allergy prevention method to be carried out with respect to a human infant, including: a first administration period (first administration step) in which to administer, to an infant, heated egg white protein in an amount of 10 mg to 20 mg per day; and a second administration period (second administration step) which is a period after the first administration period and in which to administer, to the infant, the heated egg white protein in an amount of 65 mg to 90 mg per day.