公开(公告)号：US20170333076A1

公开(公告)日：2017-11-23

申请号：US15524851

申请日：2015-11-06

申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY

发明人： Mark BRUZZI ,  Paul HENEGHAN ,  Saeid KASIRI GHAHI ,  Gerard O'SULLIVAN

IPC分类号： A61B17/3207 ,  A61B17/22 ,  A61B17/221 ,  A61B17/00 ,  A61B90/00

摘要： A thrombectomy device for removing thrombus from a body lumen comprises an elongated catheter member (2) having a distal part and a proximal part, a thrombus blocking body (5) disposed on the distal part of the catheter member and radially expansible between a contracted orientation and an expanded, thrombus-blocking, orientation, a thrombus capture body (3) disposed on the distal part of the catheter member in an axially spaced-apart relationship to the thrombus blocking body, and radially expansible between a contracted orientation and an expanded, thrombus-capture, orientation, deployment means actuable to deploy and retract the thrombus capture body and thrombus blocking body; and an elongated control arm operably connected to the thrombus capture body. The thrombus capture body is a cage having an inwardly tapering leading end, the elongated control arm is operably connected to the leading end of the cage, and a thrombus extractor or macerator mechanism is disposed within the cage.

公开(公告)号：US20210251651A1

公开(公告)日：2021-08-19

申请号：US17246353

申请日：2021-04-30

申请人： National University of Ireland Galway

发明人： Mark BRUZZI ,  Saeid KASIRI GHAHI ,  Paul HENEGHAN

IPC分类号： A61B17/3207

摘要： A thrombectomy device includes a handle at a proximal end portion of the device, a first arm connected to the handle, and a second arm extending to a distal end portion of the device. The device may also include a cage at the distal end portion of the device, the cage being adjustable between a contracted orientation and an expanded orientation, the cage including a cutting element disposed between a proximal end portion of the cage and a distal end of the cage, the cutting element including one or more of a round wire, a flat wire, or a blade configured to remove matter from a body lumen when the cage is in the expanded orientation, and a macerator extending within the first arm and the second arm, the macerator including a helical element.

公开(公告)号：US20180271556A1

公开(公告)日：2018-09-27

申请号：US15936635

申请日：2018-03-27

申请人： National University of Ireland Galway

发明人： Mark BRUZZI ,  Saeid KASIRI GHAHI ,  Paul HENEGHAN

IPC分类号： A61B17/3207 ,  A61B17/3205 ,  A61B17/221 ,  A61B17/32 ,  A61B17/00

CPC分类号： A61B17/320725 ,  A61B17/221 ,  A61B17/32056 ,  A61B17/320758 ,  A61B17/320783 ,  A61B2017/00685 ,  A61B2017/2212 ,  A61B2017/320008 ,  A61B2017/320064 ,  A61B2217/005

摘要： A device suitable for use in a body lumen and comprises an elongated control member having a distal and a proximal end, and a radially expansible member disposed at or near the distal end and adapted for collection and/or shearing of matter (i.e. thrombus) from a wall of the body lumen (i.e. a vein or an artery). The radially expansible member has a proximal end and a distal end and is adjustable between a contracted orientation and an expanded orientation. The elongated control member comprising a proximal arm connected at or adjacent to the proximal end of the radially expansible member and a distal arm connected at or adjacent to the distal end of the radially expansible member such that movement of one arm relative to the other arm effects adjustment of the diameter or radial strength of the radially expansible member. The device comprises a control mechanism operatively connected to both arms and adapted to provide resistance to the movement of one arm relative to the other. The control mechanism may be a biasing means, a brake means, or both.

公开(公告)号：US20160206344A1

公开(公告)日：2016-07-21

申请号：US15008057

申请日：2016-01-27

申请人： National University of Ireland Galway

发明人： Mark BRUZZI ,  Saeid KASIRI GHAHI ,  Paul HENEGHAN

IPC分类号： A61B17/3207 ,  A61B17/3205

CPC分类号： A61B17/320725 ,  A61B17/221 ,  A61B17/32056 ,  A61B17/320758 ,  A61B17/320783 ,  A61B2017/00685 ,  A61B2017/2212 ,  A61B2017/320008 ,  A61B2017/320064 ,  A61B2217/005

摘要： A device suitable for use in a body lumen and comprises an elongated control member having a distal and a proximal end, and a radially expansible member disposed at or near the distal end and adapted for collection and/or shearing of matter (i.e. thrombus) from a wall of the body lumen (i.e. a vein or an artery). The radially expansible member has a proximal end and a distal end and is adjustable between a contracted orientation and an expanded orientation. The elongated control member comprising a proximal arm connected at or adjacent to the proximal end of the radially expansible member and a distal arm connected at or adjacent to the distal end of the radially expansible member such that movement of one arm relative to the other arm effects adjustment of the diameter or radial strength of the radially expansible member. The device comprises a control mechanism operatively connected to both arms and adapted to provide resistance to the movement of one arm relative to the other. The control mechanism may be a biasing means, a brake means, or both.

摘要翻译： 适用于体腔的装置，包括具有远端和近端的细长控制构件，以及设置在远端处或附近的径向可膨胀构件，并适于收集和/或剪切物质（即血栓） 体腔内壁（即静脉或动脉）。 径向可膨胀构件具有近端和远端，并且在收缩取向和膨胀方向之间是可调节的。 细长的控制构件包括在径向可膨胀构件的近端处或邻近的近端臂，以及在径向可膨胀构件的远端处或邻近径向可膨胀构件的远端连接的远端臂，使得一个臂相对于另一臂的运动影响 调节径向可膨胀构件的直径或径向强度。 该装置包括可操作地连接到两个臂并且适于提供对一个臂相对于另一个臂的运动的阻力的控制机构。 控制机构可以是偏置装置，制动装置或两者。

公开(公告)号：US20210228229A1

公开(公告)日：2021-07-29

申请号：US17133111

申请日：2020-12-23

申请人： National University of Ireland Galway

发明人： Mark BRUZZI ,  Saeid KASIRI GHAHI ,  Paul HENEGHAN

IPC分类号： A61B17/3207

摘要： A thrombectomy device includes a handle at a proximal end portion of the device, a first tube connected to the handle, and a second tube extending to a distal end portion of the device. The thrombectomy device also includes a cage at the distal end portion of the device, the cage being adjustable between a contracted orientation and an expanded orientation and including a scraping element formed with one or more of a round wire, a flat wire, or a blade disposed between a proximal end portion of the cage and a distal end portion of the cage, and a suction device, including a source of suction connected to the proximal end portion of the device, the suction device being configured to apply suction towards an interior of the second tube and to an extraction passage formed between the first tube and the second tube in a radial direction.

公开(公告)号：US20210022766A1

公开(公告)日：2021-01-28

申请号：US16919924

申请日：2020-07-02

申请人： NATIONAL UNIVERSITY OF IRELAND, GALWAY

发明人： Mark BRUZZI ,  Paul HENEGHAN ,  Saeid KASIRI GHAHI ,  Gerard O'SULLIVAN

IPC分类号： A61B17/3207 ,  A61B17/22 ,  A61B17/221

摘要： A thrombectomy device for removing thrombus from a body lumen comprises an elongated catheter member (2) having a distal part and a proximal part, a thrombus blocking body (5) disposed on the distal part of the catheter member and radially expansible between a contracted orientation and an expanded, thrombus-blocking, orientation, a thrombus capture body (3) disposed on the distal part of the catheter member in an axially spaced-apart relationship to the thrombus blocking body, and radially expansible between a contracted orientation and an expanded, thrombus-capture, orientation, deployment means actuable to deploy and retract the thrombus capture body and thrombus blocking body; and an elongated control arm operably connected to the thrombus capture body. The thrombus capture body is a cage having an inwardly tapering leading end, the elongated control arm is operably connected to the leading end of the cage, and a thrombus extractor or macerator mechanism is disposed within the cage.