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公开(公告)号：US20150018553A1
公开(公告)日：2015-01-15
申请号：US14309732
申请日：2014-06-19
发明人： Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号： C07D239/54
CPC分类号： C07D239/54 , C07D239/553
摘要： The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
摘要翻译： 本发明涉及用于制备结构（VI）的促性腺激素释放激素（GnRH）受体拮抗剂的方法和中间体; 及其立体异构体及其药学上可接受的盐。
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公开(公告)号：US20180346428A1
公开(公告)日：2018-12-06
申请号：US15833513
申请日：2017-12-06
发明人： Donald J. Gallagher , Laszio R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号： C07D239/54 , C07D239/553
CPC分类号： C07D239/54 , C07D239/553
摘要： The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
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公开(公告)号：US09382214B2
公开(公告)日：2016-07-05
申请号：US14309732
申请日：2014-06-19
发明人： Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号： C07D239/02 , C07D239/54 , C07D239/553
CPC分类号： C07D239/54 , C07D239/553
摘要： The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
摘要翻译： 本发明涉及用于制备结构（VI）的促性腺激素释放激素（GnRH）受体拮抗剂的方法和中间体; 及其立体异构体及其药学上可接受的盐。
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公开(公告)号：US11459305B2
公开(公告)日：2022-10-04
申请号：US16739263
申请日：2020-01-10
发明人： Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号： C07D239/54 , C07D239/553 , A61P15/00 , A61K9/16 , A61K9/14
摘要： The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
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公开(公告)号：US20190218191A1
公开(公告)日：2019-07-18
申请号：US16020814
申请日：2018-06-27
发明人： Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号： C07D239/54 , A61P15/00
CPC分类号： C07D239/54 , A61K9/146 , A61K9/1688 , A61P15/00 , C07D239/553
摘要： The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
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公开(公告)号：US09868706B2
公开(公告)日：2018-01-16
申请号：US15406476
申请日：2017-01-13
发明人： Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号： C07D239/54 , C07D239/553
CPC分类号： C07D239/54 , C07D239/553
摘要： The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
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公开(公告)号：US20170320836A1
公开(公告)日：2017-11-09
申请号：US15406476
申请日：2017-01-13
发明人： Donald J. Gallagher , Laszlo R. Treiber , Robert Michael Hughes , Onorato Campopiano , Peng Wang , Yuxin Zhao , Shine K. Chou , Michael Allen Ouellette , Donald Nicholas Hettinger
IPC分类号： C07D239/54 , C07D239/553
CPC分类号： C07D239/54 , C07D239/553
摘要： The present invention relates to processes and intermediates for preparing Gonadotropin-Releasing Hormone (GnRH) receptor antagonists of structure (VI); and stereoisomers and pharmaceutically acceptable salts thereof.
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