公开(公告)号：US5912254A

公开(公告)日：1999-06-15

申请号：US969635

申请日：1997-11-13

申请人： Nigel Douglas Bishop ,  Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley ,  Roger Salmon ,  Christopher Richard Ayles Godfrey

发明人： Nigel Douglas Bishop ,  Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley ,  Roger Salmon ,  Christopher Richard Ayles Godfrey

IPC分类号： C07D451/02 ,  A01N43/90 ,  A01N47/38 ,  C07D451/04 ,  C07D451/14 ,  C07D498/08 ,  C07D513/08 ,  C07D519/00 ,  A61K31/435 ,  C07D221/02

CPC分类号： C07D519/00 ,  A01N43/90 ,  A01N47/38

摘要： A compound of formula (I):P-R.sup.2 -Q (I)where each of P and Q is, independently, a group of formula (B): ##STR1## wherein J is a bidentate group of formula --CH.sub.2 --X--CH.sub.2 --(wherein X is methylene, sulfur or oxygen), X'C.dbd.CY or X'WC-CYZ (wherein X', W, Y and Z are independently hydrogen, hydroxy, acyloxy, alkoxy, alkylsilyloxy or halogen); R.sup.1 is an optionally substituted phenyl or 5-or 6-membered heterocyclic ring system containing from 1 to 3 heteroatoms individually selected from nitrogen, oxygen and sulfur atoms, and at least one unsaturation (double bond) between adjacent atoms in the ring, said heterocyclic ring being optionally fused to a benzene ring; or an acid addition salt, quaternary ammonium salt or N-oxide derived therefrom; an insecticidal, acaricidal or nematicidal composition comprising a compound of formula (I) and a suitable carrier or diluent therefor; a method of combating and controlling insect, acarine or nematode pests at a locus which comprises treating the pests or the locus of the pests with an effective amount of a compound of formula (I) or a composition as hereinbefore described.

摘要翻译： 式（I）化合物：P-R 2 -Q（I）其中P和Q各自独立地是式（B）的基团：其中J是式-CH 2 -X-CH 2 - （ 其中X是亚甲基，硫或氧），X'C = CY或X'WC-CYZ（其中X'，W，Y和Z独立地是氢，羟基，酰氧基，烷氧基，烷基甲硅烷氧基或卤素）; R1是任选取代的苯基或5-或6-元杂环系，其含有1-3个分别选自氮，氧和硫原子的杂原子，以及环中相邻原子之间的至少一个不饱和键（双键），所述杂环 环任选地与苯环稠合; 或由其衍生的酸加成盐，季铵盐或N-氧化物; 杀虫杀螨或杀线虫组合物，其包含式（I）化合物及其合适的载体或稀释剂; 一种防治昆虫，螨虫或线虫害虫的方法，包括用有效量的式（I）化合物或上述组合物处理害虫或害虫的场所。

公开(公告)号：US6066646A

公开(公告)日：2000-05-23

申请号：US248930

申请日：1999-02-12

申请人： Nigel Douglas Bishop ,  Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley ,  Roger Salmon ,  Christopher Richard Ayles Godfrey

发明人： Nigel Douglas Bishop ,  Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley ,  Roger Salmon ,  Christopher Richard Ayles Godfrey

IPC分类号： C07D451/02 ,  A01N43/90 ,  A01N47/38 ,  C07D451/04 ,  C07D451/14 ,  C07D498/08 ,  C07D513/08 ,  C07D519/00 ,  A61K31/435 ,  C07D221/02

CPC分类号： C07D519/00 ,  A01N43/90 ,  A01N47/38

摘要： A compound of formula (I):P--R.sup.2 --Q (I)where each of P and Q is, independently, a group of formula (B): ##STR1## wherein J is a bidentate group of formula --CH.sub.2 --X--CH.sub.2 -- (wherein X is methylene, sulfur or oxygen), X'C.dbd.CY or X'WC--CYZ (wherein X', W, Y and Z are independently hydrogen, hydroxy, acyloxy, alkoxy, alkylsilyloxy or halogen); R.sup.1 is an optionally substituted phenyl or 5-or 6-membered heterocyclic ring system containing from 1 to 3 heteroatoms individually selected from nitrogen, oxygen and sulfur atoms, and at least one unsaturation (double bond) between adjacent atoms in the ring, said heterocyclic ring being optionally fused to a benzene ring, wherein the substutuents, if present, are selected from halogen atoms, cyano, alkyl, alkenyl, alkynyl, alkoxy, haloalkyl, haloalkenyl, alkylthio and alkyl amino groups, any of which groups contain up to six carbon atoms; R.sup.2 is a bidentate linking group and is a substituted or unsubstituted alkylene, alkylenearyl, alkyleneheteroaryl, alkenylene, alkylenylarylalkylenyl, carbonyl or diacyl group, provided that when R.sup.2 is alkenylene or alkylenylarylalkylenyl said group does not have an unsaturated carbon atom bonding directly to the ring nitrogen of formula (B); R.sup.3 is hydrogen, cyano, hydroxy, alkyl, alkoxy, amino, nitro, isocyanato, acylamino, hydroxyalkyl, optionally substituted heteroaryl, alkoxyalkyl, haloalkyl, halohydroxyalkyl, aralkyloxyalkyl, acyloxyalkyl, amidoximido, sulfonyloxyalkyl, aminoalkyl, alkoxycarbonylamino, acylaminoalkyl, cyanoalkyl, imino, formyl, acyl or carboxylic acid or an ester or amide thereof, or alkenyl or alkynyl either of which is optionally substituted by halogen, alkoxy, cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl or cyano; or an acid addition salt, quaternary ammonium salt or N-oxide derived therefrom; an insecticidal, acaricidal or nematicidal composition comprising (I).

公开(公告)号：US06174894B1

公开(公告)日：2001-01-16

申请号：US09357749

申请日：1999-07-21

申请人： Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley ,  Roger Salmon ,  Christopher Richard Ayles Godfrey ,  Christopher Ian Brightwell

发明人： Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley ,  Roger Salmon ,  Christopher Richard Ayles Godfrey ,  Christopher Ian Brightwell

IPC分类号： A61K31435

CPC分类号： C07D451/02 ,  A01N43/90 ,  A01N47/16 ,  A01N47/18 ,  C07D451/04 ,  C07D451/06 ,  C07D451/14

摘要： The present invention provides a compound of Formula (I): wherein Ar is optionally substituted phenyl wherein the substutuents, if present, are selected from halogen atoms, cyano, alkyl, alkenyl, alkynyl, alkoxy, haloalkyl, haloalkenyl, alkylthio and alkyl amino groups; R represents hydrogen or cyano or a group selected from alkyl, aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, alkoxycarbonyl, alkanesulfonyl, arenesulfonyl, alkenyloxycarbonyl, aralkyloxycarbonyl, aryloxycarbonyl, heterocyclylalkyl, carbamyl, dithiocarboxyl or XR3 (where X represents oxygen or a group NR4); R3 and R4 are, independently, hydrogen, alkyl, aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, heterocyclylalkyl, alkoxycarbonyl or carboxylic acyl each of which may be optionally substituted; R1 represents hydrogen, hydroxy, alkyl, alkoxy, amino, nitro, isocyanato, acylamino, hydroxyalkyl, optionally substituted heteroaryl, alkoxyalkyl, haloalkyl, halohydroxyalkyl, aralkyloxyalkyl, acyloxyalkyl, amidoximido, sulfonyloxyalkyl, aminoalkyl, alkoxycarbonylamino, acylaminoalkyl, cyanoalkyl, imino, formyl, acyl or carboxylic acid or an ester or amide thereof, or alkenyl or alkynyl either of which is optionally substituted; or an acid addition salt, quaternary ammonium salt or N-oxide derived therefrom; an insecticidal, acaricidal or nematicidal composition comprising a compound of formula (I) and a suitable carrier or diluent therefor; and a method of combating and controlling insect, acarine or nematode pests at a locus which comprises treating the pests or the locus of the pests with an effective amount of a compound of formula (I) or a composition as hereinbefore described.

摘要翻译： 本发明提供式（I）的化合物：其中Ar是任选取代的苯基，其中如果存在这些取代基，则选自卤素原子，氰基，烷基，烯基，炔基，烷氧基，卤代烷基，卤代烯基，烷硫基和烷基氨基 ; R表示氢或氰基或选自烷基，芳基，杂芳基，芳烷基，杂芳基烷基，烯基，芳烯基，炔基，烷氧基羰基，链烷磺酰基，芳烃磺酰基，烯氧基羰基，芳烷氧基羰基，芳氧基羰基，杂环基烷基，氨基甲酰基，二硫代羧基或XR3（其中X表示氧 或NR4组）; R 3和R 4独立地是氢，烷基，芳基，杂芳基，芳烷基，杂芳基烷基，烯基，芳烯基，炔基，杂环基烷基，烷氧基羰基或羧酰基，各自可以任选被取代; R 1表示氢，羟基，烷基，烷氧基，氨基，硝基，异氰酸酯基，酰氨基，羟基烷基，任选取代的杂芳基，烷氧基烷基，卤代烷基，卤代羟烷基，芳烷氧基烷基，酰氧基烷基，酰氨基亚氨基，磺酰氧基烷基，氨基烷基，烷氧基羰基氨基，酰氨基烷基，氰基烷基，亚氨基，甲酰基， 酰基或羧酸或其酯或酰胺，或任选被取代的链烯基或炔基; 或由其衍生的酸加成盐，季铵盐或N-氧化物; 杀虫杀螨或杀线虫组合物，其包含式（I）化合物及其合适的载体或稀释剂; 以及一种防治昆虫，螨虫或线虫害虫的场所的方法，包括用有效量的式（I）化合物或上述组合物处理害虫或害虫的场所。

公开(公告)号：US06291474B1

公开(公告)日：2001-09-18

申请号：US09635879

申请日：2000-08-10

申请人： Christopher Ian Brightwell ,  Christopher Richard Ayles Godfrey ,  Christopher John Urch ,  Matthew Brian Hotson ,  Raymond Leo Sunley ,  Roger Salmon ,  Terence Lewis

发明人： Christopher Ian Brightwell ,  Christopher Richard Ayles Godfrey ,  Christopher John Urch ,  Matthew Brian Hotson ,  Raymond Leo Sunley ,  Roger Salmon ,  Terence Lewis

IPC分类号： A61K31435

CPC分类号： C07D451/02 ,  A01N43/90 ,  A01N47/16 ,  A01N47/18 ,  C07D451/04 ,  C07D451/06 ,  C07D451/14

摘要： The invention provides a compound of formula (I): wherein A is CH═CH; Ar is an optionally substituted 5-membered heterocyclic ring system containing from 1 to 3 heteroatoms individually selected from nitrogen, oxygen and sulfur atoms, and at least one unsaturation (double bond) between adjacent atoms in the ring, said heterocyclic ring being optionally fused to a benzene ring, and R′ is hydrogen, cyano, hydroxy, alkyl, alkoxy, amino, nitro, isocyanato, acylamino, hydroxyalkyl, optionally substituted heteroaryl, alkoxyalkyl, haloalkyl, halohydroxyalkyl, aralkyloxyalkyl, acyloxyalkyl, amidoximido, sulfonyloxyalkyl, aminoalkyl, alkoxycarbonylamino, acylaminoalkyl, cyanoalkyl, imino, formyl, acyl or carboxylic acid or an ester or amide thereof, or alkenyl or alkynyl either of which is optionally substituted by halogen, alkoxy, cycloalkyl, optionally substituted aryl, optionally substituted heteroaryl or cyano; or an acid addition salt, quaternary ammonium salt or N-oxide derived therefrom; an insecticidal, acaricidal or nematicidal composition comprising a compound of formula (I) and a suitable carrier or diluent therefor; a method of combating and controlling insect, acarine or nematode pests at a locus which comprises treating the pests or the locus of the pests with an effective amount of a compound of formula (I) or a composition as hereinbefore described.

摘要翻译： 本发明提供式（I）化合物：其中A为CH = CH; Ar是任选取代的5元杂环系统，其含有1-3个分别选自氮，氧和硫原子的杂原子，以及环中相邻原子之间的至少一个不饱和键（双键），所述杂环任选地与 苯环，R'是氢，氰基，羟基，烷基，烷氧基，氨基，硝基，异氰酸根合，酰氨基，羟基烷基，任选取代的杂芳基，烷氧基烷基，卤代烷基，卤代羟烷基，芳烷氧基烷基，酰氧基烷基，酰氨基亚氨基，磺酰氧基烷基，氨基烷基，烷氧基羰基氨基， 酰基氨基烷基，氰基烷基，亚氨基，甲酰基，酰基或羧酸或其酯或酰胺，或任选被卤素，烷氧基，环烷基，任选取代的芳基，任选取代的杂芳基或氰基取代的链烯基或炔基; 或由其衍生的酸加成盐，季铵盐或N-氧化物; 杀虫杀螨或杀线虫组合物，其包含式（I）化合物及其合适的载体或稀释剂; 一种防治昆虫，螨虫或线虫害虫的方法，包括用有效量的式（I）化合物或上述组合物处理害虫或害虫的场所。

公开(公告)号：US06177442B1

公开(公告)日：2001-01-23

申请号：US09357750

申请日：1999-07-21

申请人： Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley ,  Roger Salmon ,  Christopher Richard Ayles Godfrey ,  Christopher Ian Brightwell ,  Matthew Brian Hotson

发明人： Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley ,  Roger Salmon ,  Christopher Richard Ayles Godfrey ,  Christopher Ian Brightwell ,  Matthew Brian Hotson

IPC分类号： A61K3146

CPC分类号： C07D451/02 ,  A01N43/90 ,  A01N47/16 ,  A01N47/18 ,  C07D451/04 ,  C07D451/06 ,  C07D451/14

摘要： The invention provides a compound of formula (I): wherein A represents a bidentate group of formula —CH2—X—CH2— (wherein X is methylene, sulfur or oxygen), X′C═CY or X′WC—CYZ (wherein X′, W, Y and Z are independently hydrogen, hydroxy, acyloxy, alkoxy, alkylsilyloxy, cyano or halogen, or X′ and W or Y and Z together with the carbon to which they are attached form a carbonyl group), provided that A is not CH2—CH2; Ar is an optionally substituted phenyl or 5- or 6-membered heterocyclic ring system containing from 1 to 3 heteroatoms individually selected from nitrogen, oxygen and sulfur atoms, and at least one unsaturation (double bond) between adjacent atoms in the ring, said heterocyclic ring being optionally fused to a benzene ring; aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, alkoxycarbonyl, alkanesulfonyl, arenesulfonyl, alkanyloxycarbonyl, aralkyloxycarbonyl, aryloxycarbonyl, heterocyclylalkyl, carbamyl, dithiocarboxyl moieties of R, R3 and R4 comprise from 1 to 15 carbon atoms, and are optionally substituted with one or more substituents selected from, halogen, cyano, carboxyl, carboxylic acyl, carbamyl, alkoxycarbonyl, alkoxy, alkylenedioxy, hydroxy, nitro, haloalkyl, alkyl, amino, acylamino, imidate and phosphonato groups; or an acid addition salt, quaternary ammonium salt or N-oxide derived therefrom; an insecticidal, acaricidal or nematicidal composition comprising a compound of formula (I) and a suitable carrier or diluent therefor; a method of combating and controlling insect, acarine or nematode pests at a locus which comprises treating the pests or the locus of the pests with an effective amount of a compound of formula (I) or a composition as hereinbefore described.

摘要翻译： 本发明提供式（I）化合物：其中A表示式-CH 2 -X-CH 2 - （其中X为亚甲基，硫或氧），X'C = CY或X'WC-CYZ（其中 X'，W，Y和Z独立地为氢，羟基，酰氧基，烷氧基，烷基甲硅烷氧基，氰基或卤素，或X'和W或Y和Z与它们所连接的碳一起形成羰基） A不是CH2-CH2; Ar是任选取代的苯基或5-或6-元杂环体系，其含有1-3个分别选自氮，氧和硫原子的杂原子，以及环中相邻原子之间的至少一个不饱和键（双键），所述杂环 环任选地与苯环稠合; 芳基，杂芳基，芳烷基，杂芳基烷基，烯基，芳烯基，炔基，烷氧基羰基，链烷磺酰基，芳烃磺酰基，烷氧基羰基，芳烷氧基羰基，芳氧基羰基，杂环基烷基，氨基甲酰基，R，R3和R4的二硫代羧基部分包含1至15个碳原子， 具有一个或多个选自卤素，氰基，羧基，羧基酰基，氨基甲酰基，烷氧基羰基，烷氧基，亚烷基二氧基，羟基，硝基，卤代烷基，烷基，氨基，酰氨基，亚胺基和膦酸基的取代基。 或由其衍生的酸加成盐，季铵盐或N-氧化物; 杀虫杀螨或杀线虫组合物，其包含式（I）化合物及其合适的载体或稀释剂; 一种防治昆虫，螨虫或线虫害虫的方法，包括用有效量的式（I）化合物或上述组合物处理害虫或害虫的场所。

公开(公告)号：US06207676B1

公开(公告)日：2001-03-27

申请号：US09207195

申请日：1998-12-08

申请人： Christopher John Urch ,  Roger Salmon ,  Terence Lewis ,  Christopher Richard Ayles Godfrey ,  Martin Stephen Clough

发明人： Christopher John Urch ,  Roger Salmon ,  Terence Lewis ,  Christopher Richard Ayles Godfrey ,  Martin Stephen Clough

IPC分类号： A61K31439

CPC分类号： C07D451/02 ,  A01N43/90 ,  A01N47/16 ,  A01N47/22 ,  A01N47/38 ,  C07D401/04

摘要： A compound of formula (I): wherein R1 represents a group of formula (A) where each of W, X, Y and Z and Z represents either a group CR or the nitrogen atom, provided that not more than two of W, X, Y and Z represent the nitrogen atom and where each R present is independently selected from hydrogen and halogen atoms and cyano, amino, hydrazino, acylamino, hydroxy, alkyl, hydroxyalkyl, alkoxy, haloalkyl, haloalkoxy, alkenyl, alkenyloxy, alkoxyalkenyl, alkynyl, carboxylic acyl, alkoxycarbonyl, aryl and heterocyclyl groups, said groups comprising up to 6 carbon atoms, and wherein R2 represents hydrogen or cyano or a group selected from alkyl, aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, alkoxycarbonyl, alkanesulfonyl, arenesulfonyl, alkanyloxycarbonyl, aralkyloxycarbonyl, aryloxycarbonyl, heterocyclylalkyl, carbamyl or dithiocarboxyl groups, said groups comprising from 1 to 15 carbon atoms, said groups being optionally substituted with one or more substituents selected from, halogen, cyano, carboxyl, carboxylic acyl, carbamyl, alkoxycarbonyl, alkoxy, alkylenedioxy, hydroxy, nitro, haloalkyl, alkyl, amino, acylamino, imidate and phosphonato groups; and acid addition salts and quaternary ammonium salts and N-oxide derived therefrom. The compounds are useful as insecticides.

摘要翻译： 式（I）的化合物：其中R 1表示式（A）的基团，其中W，X，Y和Z和Z各自表示基团CR或氮原子，条件是不大于2个W，X ，Y和Z代表氮原子，其中每个R独立地选自氢和卤素原子和氰基，氨基，肼基，酰氨基，羟基，烷基，羟基烷基，烷氧基，卤代烷基，卤代烷氧基，烯基，烯氧基，烷氧基烯基，炔基， 羧基酰基，烷氧基羰基，芳基和杂环基，所述基团包含至多6个碳原子，并且其中R 2表示氢或氰基或选自烷基，芳基，杂芳基，芳烷基，杂芳基烷基，烯基，芳烯基，炔基，烷氧基羰基，链烷磺酰基 ，芳基磺酰基，烷氧基羰基，芳烷氧基羰基，芳氧基羰基，杂环基烷基，氨基甲酰基或二硫代羧基，​​所述基团包含1至15个碳原子，所述基团任选被一个或多个取代基se 由卤素，氰基，羧基，羧基酰基，氨基甲酰基，烷氧基羰基，烷氧基，亚烷基二氧基，羟基，硝基，卤代烷基，烷基，氨基，酰氨基，亚氨酸酯和膦酸酯基组成。 和酸加成盐和季铵盐和由其衍生的N-氧化物。 这些化合物可用作杀虫剂。

公开(公告)号：US5922732A

公开(公告)日：1999-07-13

申请号：US651182

申请日：1996-05-24

申请人： Christopher John Urch ,  Roger Salmon ,  Terence Lewis ,  Christopher Richard Ayles Godfrey ,  Martin Stephen Clough

发明人： Christopher John Urch ,  Roger Salmon ,  Terence Lewis ,  Christopher Richard Ayles Godfrey ,  Martin Stephen Clough

IPC分类号： A01N43/42 ,  A01N43/90 ,  A01N47/16 ,  A01N47/22 ,  A01N47/38 ,  C07D401/04 ,  C07D451/02 ,  A61K31/44

CPC分类号： C07D451/02 ,  A01N43/90 ,  A01N47/16 ,  A01N47/22 ,  A01N47/38 ,  C07D401/04

摘要： A compound of formula (I): ##STR1## wherein R.sup.1 represents a group of formula (A) where each of W, X, Y and Z and Z represents either a group CR or the nitrogen atom, provided that not more than two of W, X, Y and Z represent the nitrogen atom and where each R present is independently selected from hydrogen and halogen atoms and cyano, amino, hydrazino, acylamino, hydroxy, alkyl, hydroxyalkyl, alkoxy, haloalkyl, haloalkoxy, alkenyl, alkenyloxy, alkoxyalkenyl, alkynyl, carboxylic acyl, alkoxycarbonyl, aryl and heterocyclyl groups, said groups comprising up to 6 carbon atoms, and wherein R.sup.2 represents hydrogen or cyano or a group selected from alkyl, aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, alkoxycarbonyl, alkanesulfonyl, arenesulfonyl, alkanyloxycarbonyl, aralkyloxycarbonyl, aryloxycarbonyl, heterocyclylalkyl, carbamyl or dithiocarboxyl groups, said groups comprising from 1 to 15 carbon atoms, said groups being optionally substituted with one or more substituents selected from, halogen, cyano, carboxyl, carboxylic acyl, carbamyl, alkoxycarbonyl, alkoxy, alkylenedioxy, hydroxy, nitro, haloalkyl, alkyl, amino, acylamino, imidate and phosphonato groups; and acid addition salts and quaternary ammonium salts and N-oxides derived therefrom. The compounds are useful as insecticides.

摘要翻译： 式（I）的化合物：其中R 1表示式（A）的基团，其中W，X，Y和Z和Z各自表示基团CR或氮原子，条件是不大于2个W，X ，Y和Z代表氮原子，其中每个R独立地选自氢和卤素原子和氰基，氨基，肼基，酰氨基，羟基，烷基，羟基烷基，烷氧基，卤代烷基，卤代烷氧基，烯基，烯氧基，烷氧基烯基，炔基， 羧基酰基，烷氧基羰基，芳基和杂环基，所述基团包含至多6个碳原子，并且其中R 2表示氢或氰基或选自烷基，芳基，杂芳基，芳烷基，杂芳基烷基，烯基，芳烯基，炔基，烷氧基羰基，链烷磺酰基 ，芳基磺酰基，烷氧基羰基，芳烷氧基羰基，芳氧基羰基，杂环基烷基，氨基甲酰基或二硫代羧基，​​所述基团包含1至15个碳原子，所述基团任选被一个或多个取代基 选自卤素，氰基，羧基，羧基酰基，氨基甲酰基，烷氧基羰基，烷氧基，亚烷基二氧基，羟基，硝基，卤代烷基，烷基，氨基，酰氨基，亚胺基和膦酸酯基。 和酸加成盐和季铵盐和由其衍生的N-氧化物。 这些化合物可用作杀虫剂。

公开(公告)号：US06573275B1

公开(公告)日：2003-06-03

申请号：US10124696

申请日：2002-04-12

申请人： Christopher John Urch ,  Roger Salmon ,  Terence Lewis ,  Christopher Richard Ayles Godfrey ,  Martin Stephen Clough

发明人： Christopher John Urch ,  Roger Salmon ,  Terence Lewis ,  Christopher Richard Ayles Godfrey ,  Martin Stephen Clough

IPC分类号： C07D23924

CPC分类号： C07D451/02 ,  A01N43/90 ,  A01N47/16 ,  A01N47/22 ,  A01N47/38 ,  C07D401/04

摘要： A compound of formula (I): wherein R1 represents a group of formula (A) where each of W, X, Y and Z and Z represents either a group CR or the nitrogen atom, provided that not more than two of W, X, Y and Z represent the nitrogen atom and where each R present is independently selected from hydrogen and halogen atoms and cyano, amino, hydrazino, acylamino, hydroxy, alkyl, hydroxyalkyl, alkoxy, haloalkyl, haloalkoxy, alkenyl, alkenyloxy, alkoxyalkenyl, alkynyl, carboxylic acyl, alkoxycarbonyl, aryl and heterocyclyl groups, said groups comprising up to 6 carbon atoms, and wherein R2 represents hydrogen or cyano or a group selected from alkyl, aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, alkoxycarbonyl, alkanesulfonyl, arenesulfonyl, alkanyloxycarbonyl, aralkyloxycarbonyl, aryloxycarbonyl, heterocyclylalkyl, carbamyl or dithiocarboxyl groups, said groups comprising from 1 to 15 carbon atoms, said groups being optionally substituted with one or more substituents selected from, halogen, cyano, carboxyl, carboxylic acyl, carbamyl, alkoxycarbonyl, alkoxy, alkylenedioxy, hydroxy, nitro, haloalkyl, alkyl, amino, acylamino, imidate and phosphonato groups; and acid addition salts and quaternary ammonium salts and N-oxide derived therefrom. The compounds are useful as insecticides.

公开(公告)号：US06391883B1

公开(公告)日：2002-05-21

申请号：US09602711

申请日：2000-06-26

申请人： Christopher John Urch ,  Roger Salmon ,  Terence Lewis ,  Christopher Richard Ayles Godfrey ,  Martin Stephen Clough

发明人： Christopher John Urch ,  Roger Salmon ,  Terence Lewis ,  Christopher Richard Ayles Godfrey ,  Martin Stephen Clough

IPC分类号： A61K31497

CPC分类号： C07D451/02 ,  A01N43/90 ,  A01N47/16 ,  A01N47/22 ,  A01N47/38 ,  C07D401/04

摘要： A compound of formula (I): wherein R1 represents a group of formula (A) where each of W, X, Y and Z and Z represents either a group CR or the nitrogen atom, provided that not more than two of W, X, Y and Z represent the nitrogen atom and where each R present is independently selected from hydrogen and halogen atoms and cyano, amino, hydrazino, acylamino, hydroxy, alkyl, hydroxyalkyl, alkoxy, haloalkyl, haloalkoxy, alkenyl, alkenyloxy, alkoxyalkenyl, alkynyl, carboxylic acyl, alkoxycarbonyl, aryl and heterocyclyl groups, said groups comprising up to 6 carbon atoms, and wherein R2 represents hydrogen or cyano or a group selected from alkyl, aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, alkoxycarbonyl, alkanesulfonyl, arenesulfonyl, alkanyloxycarbonyl, aralkyloxycarbonyl, aryloxycarbonyl, heterocyclylalkyl, carbamyl or dithiocarboxyl groups, said groups comprising from 1 to 15 carbon atoms, said groups being optionally substituted with one or more substituents selected from, halogen, cyano, carboxyl, carboxylic acyl, carbamyl, alkoxycarbonyl, alkoxy, alkylenedioxy, hydroxy, nitro, haloalkyl, alkyl, amino, acylamino, imidate and phosphonato groups; and acid addition salts and quaternary ammonium salts and N-oxide derived therefrom. The compounds are useful as insecticides.

摘要翻译： 式（I）的化合物：其中R 1表示式（A）的基团，其中W，X，Y和Z和Z各自表示基团CR或氮原子，条件是不大于2个W，X ，Y和Z代表氮原子，其中每个R独立地选自氢和卤素原子和氰基，氨基，肼基，酰氨基，羟基，烷基，羟基烷基，烷氧基，卤代烷基，卤代烷氧基，烯基，烯氧基，烷氧基烯基，炔基， 羧基酰基，烷氧基羰基，芳基和杂环基，所述基团包含至多6个碳原子，并且其中R 2表示氢或氰基或选自烷基，芳基，杂芳基，芳烷基，杂芳基烷基，烯基，芳烯基，炔基，烷氧基羰基，链烷磺酰基 ，芳基磺酰基，烷氧基羰基，芳烷氧基羰基，芳氧基羰基，杂环基烷基，氨基甲酰基或二硫代羧基，​​所述基团包含1至15个碳原子，所述基团任选被一个或多个取代基se 由卤素，氰基，羧基，羧基酰基，氨基甲酰基，烷氧基羰基，烷氧基，亚烷基二氧基，羟基，硝基，卤代烷基，烷基，氨基，酰氨基，亚氨酸酯和膦酸酯基组成。 和酸加成盐和季铵盐和由其衍生的N-氧化物。 这些化合物可用作杀虫剂。

公开(公告)号：US5849754A

公开(公告)日：1998-12-15

申请号：US969634

申请日：1997-11-13

申请人： Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley

发明人： Christopher John Urch ,  Terence Lewis ,  Raymond Leo Sunley

IPC分类号： A01N43/90 ,  C07D451/02 ,  A61K31/46 ,  C07D401/04 ,  C07D409/04 ,  C07D411/04

CPC分类号： C07D451/02 ,  A01N43/90

摘要： The present invention concerns bicyclic amine derivatives of formula (I): ##STR1## wherein R.sup.1 is an optionally substituted 5-membered heterocyclic ring system containing from 1 to 3 heteroatoms individually selected from nitrogen, oxygen and sulfur atoms, and at least one unsaturation (double bond) between adjacent atoms in the ring, wherein the substutuents, if present, are selected from halogen atoms, alkyl, alkenyl, alkynyl, alkoxy, haloalkyl, haloalkenyl, alkylthio and alkyl amino groups, any of which groups contain up to eight carbon atoms, and wherein two substituents may join to form a fused ring; R.sup.2 represents hydrogen or cyano or a group selected from alkyl, aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, alkoxycarbonyl, alkanesulfonyl, arenesulfonyl, alkenyloxycarbonyl, aralkyloxycarbonyl, aryloxycarbonyl, heterocyclylalkyl, carbamyl, dithiocarboxyl or XR.sup.3 (where X represents oxygen or a group NR.sup.4), provided that when R.sup.2 is alkenyl, aralkenyl or alkynyl said group does not have an unsaturated carbon atom bonding directly to the ring nitrogen of formula (I); R.sup.3 and R.sup.4 are, independently, hydrogen, alkyl, aryl, heteroaryl, aralkyl, heteroarylalkyl, alkenyl, aralkenyl, alkynyl, heterocyclylalkyl, alkoxycarbonyl or carboxylic acyl; alkyl moieties of R.sup.2, R.sup.3 and R.sup.4 comprise from 1 to 15 carbon atoms, and are optionally substituted with one or more substituents selected from, halogen, cyano, carboxyl, carboxylic acyl, carbamyl, alkoxycarbonyl, alkoxy, alkylenedioxy, hydroxy, nitro, haloalkyl, alkyl, amino, acylamino, imidate and phosphonato groups; or an acid addition salt, quaternary ammonium salt or N-oxide derived therefrom; to processes for preparing them, to insecticidal compositions comprising them and to methods of using them to combat and control insect pests.

摘要翻译： 本发明涉及式（I）的双环胺衍生物：其中R 1是含有1至3个选自氮，氧和硫原子的杂原子的任选取代的5元杂环体系，至少 烷基，烯基，炔基，烷氧基，卤代烷基，卤代烯基，烷硫基和烷基氨基，其中任何一个基团都包含上述基团 至8个碳原子，并且其中两个取代基可以连接形成稠环; R 2表示氢或氰基或选自烷基，芳基，杂芳基，芳烷基，杂芳基烷基，烯基，芳烯基，炔基，烷氧基羰基，链烷磺酰基，芳烃磺酰基，链烯氧基羰基，芳烷氧基羰基，芳氧基羰基，杂环基烷基，氨基甲酰基，二硫代羧基或XR3（其中X表示氧 或基团NR4），条件是当R 2为烯基时，所述基团不具有与式（I）的环氮直接键合的不饱和碳原子。 R 3和R 4独立地是氢，烷基，芳基，杂芳基，芳烷基，杂芳基烷基，烯基，芳烯基，炔基，杂环基烷基，烷氧基羰基或羧基酰基。 R 2，R 3和R 4的烷基部分包含1至15个碳原子，并且任选地被一个或多个选自卤素，氰基，羧基，羧基酰基，氨基甲酰基，烷氧基羰基，烷氧基，亚烷基二氧基，羟基，硝基，卤代烷基 ，烷基，氨基，酰氨基，亚氨酸酯和膦酰基; 或由其衍生的酸加成盐，季铵盐或N-氧化物; 制备它们的方法，包含它们的杀虫组合物以及使用它们来对抗和控制害虫的方法。