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公开(公告)号：US11406598B2
公开(公告)日：2022-08-09
申请号：US17025881
申请日：2020-09-18
发明人： Bala Tripura Sundari Chodavarapu , Thirupathi Mangali , Jay Shukla , Anand Shukla , Dasaradhi Lakkaraju
IPC分类号： A61K9/19 , A61K31/515 , A61K9/00
摘要： A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.
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公开(公告)号：US20220354794A1
公开(公告)日：2022-11-10
申请号：US17854914
申请日：2022-06-30
发明人： Bala Tripura Sundari Chodavarapu , Thirupathi Mangali , Jay Shukla , Anand Shukla , Dasaradhi Lakkaraju
IPC分类号： A61K9/19 , A61K31/515 , A61K47/02
摘要： A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenyl ethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.
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公开(公告)号：US20210085608A1
公开(公告)日：2021-03-25
申请号：US17025881
申请日：2020-09-18
发明人： Bala Tripura Sundari Chodavarapu , Thirupathi Mangali , Jay Shukla , Anand Shukla , Dasaradhi Lakkaraju
IPC分类号： A61K9/19 , A61K9/00 , A61K31/515
摘要： A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.
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公开(公告)号：US20230043597A1
公开(公告)日：2023-02-09
申请号：US17871058
申请日：2022-07-22
发明人： Thirupathi Mangali , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jay Shukla , Dasaradhi Lakkaraju
摘要： Described is an aqueous calcium gluconate solution formulated without calcium saccharate, which can be stored in a flexible plastic bag and can be terminally sterilized.
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公开(公告)号：US20210369673A1
公开(公告)日：2021-12-02
申请号：US17331011
申请日：2021-05-26
发明人： Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Niravkumar Prajapati , Anand Shukla , Jay Shukla
IPC分类号： A61K31/4035 , A61K47/24 , A61K47/26 , A61K47/14 , A61K47/38
摘要： Compositions of a stabilized chlorthalidone suspension and methods for making a stabilized chlorthalidone suspension include chlorthalidone along with a solubilizing and/or wetting agent, a suspending agent, and a viscosity increasing agent and/or an anti-caking agent, wherein the stabilized chlorthalidone suspension is a uniform dispersion with consistent concentration of chlorthalidone throughout the composition and storage.
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公开(公告)号：US11957658B2
公开(公告)日：2024-04-16
申请号：US17331011
申请日：2021-05-26
发明人： Govind R. Jagadale , Dasaradhi Lakkaraju , Bala Tripura Sundari Chodavarapu , Niravkumar Prajapati , Anand Shukla , Jay Shukla
IPC分类号： A61K31/4035 , A61K47/14 , A61K47/24 , A61K47/26 , A61K47/38
CPC分类号： A61K31/4035 , A61K47/14 , A61K47/24 , A61K47/26 , A61K47/38
摘要： Compositions of a stabilized chlorthalidone suspension and methods for making a stabilized chlorthalidone suspension include chlorthalidone along with a solubilizing and/or wetting agent, a suspending agent, and a viscosity increasing agent and/or an anti-caking agent, wherein the stabilized chlorthalidone suspension is a uniform dispersion with consistent concentration of chlorthalidone throughout the composition and storage.
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公开(公告)号：US11878076B2
公开(公告)日：2024-01-23
申请号：US18100804
申请日：2023-01-24
发明人： Bala Tripura Sundari Chodavarapu , Thirupathi Mangali , Jay Shukla , Anand Shukla , Dasaradhi Lakkaraju
IPC分类号： A61K9/19 , A61K47/02 , A61K31/515
CPC分类号： A61K9/19 , A61K31/515 , A61K47/02
摘要： A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.
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公开(公告)号：US12115187B1
公开(公告)日：2024-10-15
申请号：US18667826
申请日：2024-05-17
发明人： Niravbhai Jayantibhai Patel , Robert Miller , Maheshkumar Kalubhai Bhalaria , Rucha Abhijit Kelekar , Brijeshkumar B Pandya , Sunil Dnyanu Khandekar , Sudhir Shantarum Jagdale , Dasaradhi Lakkaraju , Jay Shukla
CPC分类号： A61K33/42 , A61J1/10 , A61K9/0019 , A61K9/08
摘要： Ready-to-use (RTU) Sodium Phosphates solutions for phosphorus replacement therapy are presented that include Sodium phosphate with/without sodium chloride at a fixed volume with 1.5 to 15 mmol/100 mL phosphorus, no more than 20 mEq/100 mL Sodium and less than 50 mcg/L aluminum.
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公开(公告)号：US11672823B2
公开(公告)日：2023-06-13
申请号：US17871058
申请日：2022-07-22
发明人： Thirupathi Mangali , Bala Tripura Sundari Chodavarapu , Anand Shukla , Jay Shukla , Dasaradhi Lakkaraju
摘要： Described is an aqueous calcium gluconate solution formulated without calcium saccharate, which can be stored in a flexible plastic bag and can be terminally sterilized.
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公开(公告)号：US20230157959A1
公开(公告)日：2023-05-25
申请号：US18100804
申请日：2023-01-24
发明人： Bala Tripura Sundari Chodavarapu , Thirupathi Mangali , Jay Shukla , Anand Shukla , Dasaradhi Lakkaraju
IPC分类号： A61K9/19 , A61K47/02 , A61K31/515
CPC分类号： A61K9/19 , A61K47/02 , A61K31/515
摘要： A composition of, method for producing, and use of an amorphous lyophilized Phenobarbital Sodium having high purity are presented. The amorphous lyophilized Phenobarbital Sodium is storage-stable being essentially void of impurities (e.g., phenylethylacetylurea (PEAU), 2-ethyl-2-phenylmalonamide (2EPMM), and/or alpha-phenylbutyrylguanidine (PBG)) upon reconstitution in water.
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