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公开(公告)号:US20130237590A1
公开(公告)日:2013-09-12
申请号:US13810363
申请日:2011-07-14
申请人: Norman L. Eberhardt , Bryan Mciver , Stefan K.G. Grebe , Honey V. Reddi , Alicia Algeciras-Schimnich
发明人: Norman L. Eberhardt , Bryan Mciver , Stefan K.G. Grebe , Honey V. Reddi , Alicia Algeciras-Schimnich
IPC分类号: A61K31/7088
CPC分类号: A61K31/7088 , C12Q1/6886 , C12Q2600/112 , C12Q2600/118 , C12Q2600/158 , C12Q2600/178
摘要: This document provides methods and materials involved in assessing thyroid neoplasms. For example, methods and materials for using microRNA (miR) levels (e.g., miR122 levels) to determine whether a thyroid neoplasm (e.g., a follicular thyroid neoplasm) is benign or malignant as well as methods and materials for using miR levels (e.g., miR122 levels) to determine whether a malignant thyroid cancer patient is likely to have a favorable or unfavorable outcome are provided. This document also provides methods and materials involved in treating cancer.
摘要翻译: 本文档提供了评估甲状腺肿瘤的方法和材料。 例如,使用microRNA(miR)水平(例如miR122水平)来确定甲状腺肿瘤(例如,滤泡性甲状腺肿瘤)是良性还是恶性的方法和材料以及使用miR水平的方法和材料(例如, miR122水平)以确定恶性甲状腺癌患者是否可能具有有利或不利的结果。 本文件还提供了治疗癌症的方法和材料。
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公开(公告)号:US20090226925A1
公开(公告)日:2009-09-10
申请号:US12424087
申请日:2009-04-15
申请人: Stefan K.G. Grebe , Mark R. Pittelkow , Kevin C. Halling , Aleksandar Sekulic , Kendall W. Cradic , Ming Mai
发明人: Stefan K.G. Grebe , Mark R. Pittelkow , Kevin C. Halling , Aleksandar Sekulic , Kendall W. Cradic , Ming Mai
CPC分类号: C12Q1/6886 , C12Q2600/156
摘要: Nucleic acids and methods for amplifying and detecting mutant BRAF sequences are provided herein. In particular, nucleic acids and methods for amplifying and detecting BRAF sequences that encode the V600E BRAF mutant are provided herein.
摘要翻译: 本发明提供了用于扩增和检测突变型BRAF序列的核酸和方法。 特别地,本文提供用于扩增和检测编码V600E BRAF突变体的BRAF序列的核酸和方法。
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