公开(公告)号：US09962448B2

公开(公告)日：2018-05-08

申请号：US14431685

申请日：2013-10-04

申请人： Northeastern University

发明人： Juan Sebastian Pappalardo ,  Micaela Toniutti ,  Stefano Salmaso ,  Tatyana S. Levchenko ,  Vladimir Torchilin

IPC分类号： C07H15/02 ,  C07H15/20 ,  A61K47/48 ,  A61K38/00 ,  A61K31/74 ,  A61K31/77 ,  A61K9/127 ,  A61K39/00 ,  A61K39/002 ,  A61K39/12 ,  A61K47/54 ,  A61K47/69

CPC分类号： A61K47/6911 ,  A61K9/127 ,  A61K31/74 ,  A61K31/77 ,  A61K38/00 ,  A61K39/0005 ,  A61K39/002 ,  A61K39/12 ,  A61K47/549 ,  C07H15/02 ,  C07H15/20

摘要： Compounds and methods for targeted immune system delivery are disclosed. Pharmaceutical compositions including the disclosed compounds and a pharmaceutically acceptable excipient are also disclosed. Methods of targeted delivery to an antigen-presenting cell, and methods of treating or preventing a disease or condition susceptible to treatment by immunomodulation are disclosed.