公开(公告)号：US20190112591A1

公开(公告)日：2019-04-18

申请号：US16306563

申请日：2017-05-25

申请人： Northwestern University

发明人： Omar F. FARHA ,  Peng LI ,  Justin A. MODICA ,  Milan MRKSICH ,  Joseph T. HUPP

IPC分类号： C12N11/02 ,  C12N9/18 ,  C12N9/16 ,  A62D3/02

摘要： Enzyme-immobilizing MOFs and methods for their use in enzymatically catalyzed reactions are provided. The MOFs are channel-type MOFs that present a hierarchical pore structure comprising a first set of large channels sized for enzyme immobilization and a second set of smaller channels running alongside of the large channels that remain enzyme-free and allow for reactant delivery to the enzymes and product expulsion from the larger channels.