公开(公告)号：US20130172349A1

公开(公告)日：2013-07-04

申请号：US13774305

申请日：2013-02-22

Applicant: Novartis AG

Inventor： Ian BRUCE ,  Bernard CUENOUD ,  Thomas Hugo KELLER ,  Gaynor Elizabeth WOODWARD ,  Nicola PRESS ,  Darren Mark LE GRAND ,  Cathy RITCHIE ,  Barbara VALADE ,  Judy Fox HAYLER ,  Emma BUDD

IPC: A61K31/5377 ,  A61K31/497 ,  A61K45/06 ,  C07D417/14

CPC classification number: A61K31/5377 ,  A61K31/497 ,  A61K45/06 ,  C07D417/04 ,  C07D417/14

Abstract: Compounds of formula I in free or salt form, wherein R1, R2, R3 and R4 have the meanings as indicated in the specification, are useful for treating conditions that are mediated by phosphatidylinositol 3-kinase.Pharmaceutical compositions that contain the compounds and a process for preparing the compounds are also described.

Abstract translation: 游离或盐形式的式I化合物，其中R 1，R 2，R 3和R 4具有说明书中所示的含义，可用于治疗由磷脂酰肌醇3-激酶介导的病症。 还描述了含有化合物的药物组合物和制备该化合物的方法。