公开(公告)号：US20170198040A1

公开(公告)日：2017-07-13

申请号：US15382251

申请日：2016-12-16

Applicant: Novartis AG

Inventor： Nicole BALKE ,  Thomas CALZASCIA ,  Stefan EWERT ,  Alan HARRIS ,  Heather Adkins HUET ,  Isabelle ISNARDI ,  Haihui LU ,  Matthew John MEYER ,  Nicholas WILSON ,  Fangmin WU

IPC: C07K16/28 ,  A61K45/06

CPC classification number: C07K16/2803 ,  A61K39/395 ,  A61K45/06 ,  A61K2039/505 ,  A61K2039/507 ,  A61K2039/541 ,  A61K2039/545 ,  C07K16/28 ,  C07K16/283 ,  C07K16/2887 ,  C07K2317/31 ,  C07K2317/33 ,  C07K2317/34 ,  C07K2317/35 ,  C07K2317/41 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/71 ,  C07K2317/72 ,  C07K2317/732 ,  C07K2317/76 ,  C07K2317/92

Abstract: The present invention relates to isolated antibodies and antigen-binding fragments thereof which selectively bind human CD32b. Also provided herein are compositions comprising the antibodies or antigen-binding fragments thereof, methods of using the antibodies or antigen-binding fragments thereof, and methods of making the antibodies or antigen-binding fragments thereof.