公开(公告)号：US20230391782A1

公开(公告)日：2023-12-07

申请号：US18033100

申请日：2021-11-01

Applicant: Novartis AG

Inventor： Thomas Josef TROXLER ,  David ORAIN ,  Pascal FURET ,  Klaus WEIGAND ,  Achim SCHLAPBACH

IPC: C07D487/04 ,  C07D401/12 ,  C07D413/12 ,  C07D417/12 ,  C07D405/12

CPC classification number: C07D487/04 ,  C07D401/12 ,  C07D413/12 ,  C07D417/12 ,  C07D405/12

Abstract: The present invention relates to novel pyridine-N oxide substituted 2-formamido (N-phenyl and N-pyridyl) acetamide compounds that are Interleukin-17 (IL-17) inhibitors, processes for their preparation, pharmaceutical compositions, and medicaments containing them, and their use in diseases and disorders mediated by IL-17.