公开(公告)号：US20240208953A1

公开(公告)日：2024-06-27

申请号：US18551739

申请日：2022-03-24

Applicant: Novartis AG

Inventor： Kevin Matthew GARDINIER ,  Mark Patrick HEALY ,  Keith JENDZA ,  Yue PAN ,  Kate Yaping WANG ,  Fan YANG

IPC: C07D413/06 ,  A61K31/404 ,  A61K31/416 ,  A61K31/423 ,  A61K31/428 ,  A61K31/437 ,  A61K31/4709 ,  A61K31/536 ,  A61K31/538 ,  A61K31/5415 ,  A61K31/553 ,  C07D401/06 ,  C07D403/06 ,  C07D405/14 ,  C07D417/06 ,  C07D471/04

CPC classification number: C07D413/06 ,  A61K31/404 ,  A61K31/416 ,  A61K31/423 ,  A61K31/428 ,  A61K31/437 ,  A61K31/4709 ,  A61K31/536 ,  A61K31/538 ,  A61K31/5415 ,  A61K31/553 ,  C07D401/06 ,  C07D403/06 ,  C07D405/14 ,  C07D417/06 ,  C07D471/04

Abstract: The present disclosure provides a compound of formula (I), or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the disclosure, and its therapeutic uses. The present disclosure further provides a combination of pharmacologically active agents and a pharmaceutical composition.

公开(公告)号：US20240199576A1

公开(公告)日：2024-06-20

申请号：US18551699

申请日：2022-03-24

Applicant: Novartis AG ,  Cadent Therapeutics, Inc.

Inventor： Mark Patrick HEALY ,  Yue PAN ,  Kate Yaping WANG

IPC: C07D401/06 ,  A61K31/403 ,  A61K31/4439 ,  C07D209/52 ,  C07D401/12

CPC classification number: C07D401/06 ,  A61K31/403 ,  A61K31/4439 ,  C07D209/52 ,  C07D401/12

Abstract: The present disclosure provides a compound of formula (I), or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the disclosure, and its therapeutic uses. The present disclosure further provides a combination of pharmacologically active agents and a pharmaceutical composition.