公开(公告)号：US10919887B2

公开(公告)日：2021-02-16

申请号：US15762724

申请日：2016-09-20

Applicant: Novartis AG

Inventor： Eric Aubin ,  Anthony Casarez ,  Andreas Fisch ,  Zaixing Li ,  Mika Lindvall ,  Heinz Ernst Moser ,  Michael Mutz ,  Folkert Reck ,  Bernd Ulrich Riebesehl ,  Marc Schoenhentz ,  Vijay Sethuraman ,  Robert Lowell Simmons

IPC: C07D417/14 ,  A61P31/04

Abstract: The invention provides new solid forms, salts and polymorphs of 1-(((Z)-(1-(2-aminothiazol-4-yl)-2-oxo-2-(((3S,4R)-2-oxo-4-((2-oxooxazolidin-3-yl)methyl)-1-sulfoazetidin-3-yl)amino)ethylidene)amino)oxy)cyclopropanecarboxylic acid (referred to herein as Compound X), pharmaceutical compositions containing them, and processes for their manufacture and use in therapy.