公开(公告)号：US20180303945A1

公开(公告)日：2018-10-25

申请号：US15957474

申请日：2018-04-19

Applicant: NOVARTIS AG

Inventor： Christopher M. ADAMS ,  Myriam APRIL ,  Tanzina FAZAL ,  Cornelia Jutta FORSTER ,  Edward Charles HALL ,  Cameron Chuck-munn LEE

IPC: A61K47/36 ,  A61K47/10 ,  A61K47/22 ,  A61K31/496 ,  A61K9/00 ,  A61P27/02

Abstract: Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.

公开(公告)号：US20230201353A1

公开(公告)日：2023-06-29

申请号：US18054767

申请日：2022-11-11

Applicant: Novartis AG

Inventor： Christopher M. ADAMS ,  Myriam APRIL ,  Tanzina FAZAL ,  Cornelia Jutta FORSTER ,  Edward Charles HALL ,  Cameron Chuck-munn LEE

IPC: A61K47/36 ,  A61K47/61 ,  A61K47/69 ,  A61P27/02 ,  A61K9/00 ,  A61K31/496 ,  A61K47/10 ,  A61K47/22

CPC classification number: A61K47/36 ,  A61K47/61 ,  A61K47/6903 ,  A61P27/02 ,  A61K9/0048 ,  A61K31/496 ,  A61K47/10 ,  A61K47/22

Abstract: Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.

公开(公告)号：US20250145600A1

公开(公告)日：2025-05-08

申请号：US18836800

申请日：2023-02-10

Applicant: Novartis AG

Inventor： Martin ALLAN ,  Matthew CARSON ,  Thomas CAYA ,  Tanzina FAZAL ,  Ming QIAN ,  Troy SMITH ,  Liansheng SU ,  Lihua YANG ,  Ping ZHANG

IPC: C07D413/14 ,  A61K31/454 ,  A61K31/4545 ,  A61K45/06 ,  C07D405/14 ,  C07D417/14

Abstract: The present invention relates to compounds of formula (I): or pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising these compounds, as well as methods and uses of these compounds in the treatment of diseases.

公开(公告)号：US20220323595A1

公开(公告)日：2022-10-13

申请号：US17804217

申请日：2022-05-26

Applicant: Novartis AG

Inventor： Christopher M. ADAMS ,  Myriam APRIL ,  Tanzina FAZAL ,  Cornelia Jutta FORSTER ,  Nicole GERWIN ,  Edward Charles HALL ,  Jean-Baptiste Georges Armand LANGLOIS ,  Cameron Chuck-munn LEE

IPC: A61K47/65 ,  A61K47/54 ,  A61K47/69 ,  A61P19/02 ,  A61K47/10 ,  A61K47/18 ,  A61K47/26 ,  C07K14/515

Abstract: Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.

公开(公告)号：US20200376129A1

公开(公告)日：2020-12-03

申请号：US16901601

申请日：2020-06-15

Applicant: Novartis AG

Inventor： Christopher M. ADAMS ,  Myriam APRIL ,  Tanzina FAZAL ,  Cornelia Jutta FORSTER ,  Edward Charles HALL ,  Cameron Chuck-munn LEE

IPC: A61K47/36 ,  A61K9/00 ,  A61K31/496 ,  A61P27/02 ,  A61K47/22 ,  A61K47/61 ,  A61K47/69 ,  A61K47/10

Abstract: Described herein are drug delivery systems for delivering biologically active agents comprising primary or secondary amines, or a ring nitrogen atom of an azaheteroaryl ring, pharmaceutically acceptable salts thereof, drug delivery reagents related thereto, pharmaceutical compositions comprising the drug delivery systems, and the use of the drug delivery systems as sustained release therapeutics.