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公开(公告)号:US10722518B2
公开(公告)日:2020-07-28
申请号:US15730175
申请日:2017-10-11
Applicant: Novartis AG
Inventor: Cristina Lopez-Lopez , Ulf Neumann , Derya Shimshek
IPC: A61K31/5377 , A61P9/10
Abstract: The present invention relates to an oxazine derivative BACE-1 inhibitor and pharmaceutical compositions comprising such oxazine derivative for use in the treatment or prevention of cerebral amyloid angiopathy and, in particular, wherein the patient carries one or two copies of the ApoE4 allele.