公开(公告)号：US20240246991A1

公开(公告)日：2024-07-25

申请号：US18531320

申请日：2023-12-06

Applicant: Novartis AG

Inventor： Zhongbo Fei ,  Huanqing Jia ,  Wei Li ,  Xiaohui Lin ,  Zhongcheng Min ,  Hui Wang ,  Jianhua Wang ,  Hao Zhang

IPC: C07D491/107

CPC classification number: C07D491/107

Abstract: The present invention relates to a method for the manufacture of a compound of Formula I or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II with a compound of the formula III according to the following reaction scheme:




wherein LG, A, n, m and p are as defined in the Summary of the Invention.

公开(公告)号：US11873307B2

公开(公告)日：2024-01-16

申请号：US17280632

申请日：2019-09-18

Applicant: Novartis AG

Inventor： Zhongbo Fei ,  Huanqing Jia ,  Wei Li ,  Xiaohui Lin ,  Zhongcheng Min ,  Hui Wang ,  Jianhua Wang ,  Hao Zhang

IPC: C07D491/107

CPC classification number: C07D491/107

Abstract: The present invention relates to a method for the manufacture of a compound of Formula I or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II with a compound of the formula III according to the following reaction scheme: wherein LG, A, n, m and p are as defined in the Summary of the Invention.

公开(公告)号：US20210355134A1

公开(公告)日：2021-11-18

申请号：US17280632

申请日：2019-09-18

Applicant: Novartis AG

Inventor： Zhongbo Fei ,  Huanqing Jia ,  Wei Li ,  Xiaohui Lin ,  Zhongcheng Min ,  Hui Wang ,  Jianhua Wang ,  Hao Zhang

IPC: C07D491/107

Abstract: The present invention relates to a method for the manufacture of a compound of Formula I or a pharmaceutically acceptable salt, acid co-crystal, hydrate or other solvate thereof, said method comprising reacting a compound of the formula II with a compound of the formula III according to the following reaction scheme: wherein LG, A, n, m and p are as defined in the Summary of the Invention.