公开(公告)号：US11952574B2

公开(公告)日：2024-04-09

申请号：US18213289

申请日：2023-06-23

申请人： Novo Nordisk A/S ,  Dicerna Pharmaceuticals, Inc.

发明人： Anna Linda Blois ,  Christina Marie Priest ,  Jihye Park ,  Henryk Dudek

IPC分类号： C12N15/11 ,  A61P7/00 ,  C12N15/113

CPC分类号： C12N15/1138 ,  A61P7/00 ,  C12N2310/14 ,  C12N2310/315 ,  C12N2310/531

摘要： Oligonucleotides are provided herein that inhibit TMPRSS6 expression. Also provided are compositions including the same and uses thereof, particularly uses relating to treating diseases, disorders and/or conditions associated with hepcidin deficiency or suppression.

公开(公告)号：US20240309388A1

公开(公告)日：2024-09-19

申请号：US18441001

申请日：2024-02-14

申请人： Novo Nordisk A/S ,  Dicerna Pharmaceuticals, Inc.

发明人： Anna Linda Blois ,  Christina Marie Priest ,  Jihye Park ,  Henryk Dudek

IPC分类号： C12N15/113 ,  A61P7/00

CPC分类号： C12N15/1138 ,  A61P7/00 ,  C12N2310/14 ,  C12N2310/315 ,  C12N2310/531

摘要： Oligonucleotides are provided herein that inhibit TMPRSS6 expression. Also provided are compositions including the same and uses thereof, particularly uses relating to treating diseases, disorders and/or conditions associated with hepcidin deficiency or suppression.

公开(公告)号：US20240002858A1

公开(公告)日：2024-01-04

申请号：US18213289

申请日：2023-06-23

申请人： Novo Nordisk A/S ,  Dicerna Pharmaceuticals, Inc.

发明人： Anna Linda Blois ,  Christina Marie Priest ,  Jihye Park ,  Henryk Dudek

IPC分类号： C12N15/113 ,  A61P7/00

CPC分类号： C12N15/1138 ,  A61P7/00 ,  C12N2310/14 ,  C12N2310/315 ,  C12N2310/531

摘要： Oligonucleotides are provided herein that inhibit TMPRSS6 expression. Also provided are compositions including the same and uses thereof, particularly uses relating to treating diseases, disorders and/or conditions associated with hepcidin deficiency or suppression.