公开(公告)号：US12043626B2

公开(公告)日：2024-07-23

申请号：US17957725

申请日：2022-09-30

申请人： Nuvalent, Inc.

发明人： Sibao Chen ,  Christopher G. F. Cooper ,  Baudouin Gerard ,  Joshua Courtney Horan ,  Jason T. Kropp ,  Benjamin Stephen Lane ,  David James Pearson

IPC分类号： C07D491/22 ,  A61K9/20 ,  A61K9/28

CPC分类号： C07D491/22 ,  A61K9/2013 ,  A61K9/2018 ,  A61K9/2054 ,  A61K9/2059 ,  A61K9/2833 ,  C07B2200/13

摘要： Provided herein are solid forms comprising a compound of formula (I), or a stereoisomer, or a mixture of stereoisomers thereof, or a pharmaceutically acceptable salt thereof. Also provided herein are methods of synthesizing a compound of formula (I), pharmaceutical compositions comprising the same, and methods of treating, preventing, and managing various disorders using the compositions provided herein.