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公开(公告)号：US20230293650A1
公开(公告)日：2023-09-21
申请号：US17995780
申请日：2021-04-09
CPC分类号： A61K39/0011 , A61P35/00 , A61K2039/53 , A61K2039/6031 , A61K2039/70
摘要： The present invention relates to an individualized therapeutic anticancer vaccine, methods of treatment of cancer wherein such an anticancer vaccine is used as well as methods for producing the vaccine.
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公开(公告)号：US20230165952A1
公开(公告)日：2023-06-01
申请号：US17997407
申请日：2021-05-03
发明人： Agnete Brunsvik Fredriksen , Monika Sekelja , Karoline Schjetne , Gunnstein Norheim , Elisabeth Stubsrud
IPC分类号： A61K39/215 , A61P31/14
CPC分类号： A61K39/215 , A61P31/14 , A61K2039/6075
摘要： Disclosed is a vaccine comprising an immunologically effective amount of a polynucleotide comprising a nucleotide sequence encoding a targeting unit, a dimerization unit and an antigenic unit, wherein the antigenic unit comprises at least one betacoronavirus epitope. The vaccine is ideal for pandemic and epidemics as it can induce rapid, strong immune response with lower/fewer doses because the antigen is targeted to antigen presenting cells and the antigen is produced in the body.
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公开(公告)号：US20240173391A1
公开(公告)日：2024-05-30
申请号：US18552383
申请日：2022-03-25
发明人： Agnete Øvre Fredriksen , Karoline Schjetne , Stine Granum , Audun Trygge Haugen Bersaas , Ina Park Rhee , Siri Brinchmann-Hansen Torhaug
IPC分类号： A61K39/00 , A61K39/395 , A61K45/06 , A61P35/00 , C07K16/28
CPC分类号： A61K39/0011 , A61K39/39541 , A61K45/06 , A61P35/00 , C07K16/2803 , C07K16/2818 , C07K16/2827 , A61K2039/505 , A61K2039/53 , A61K2039/6056 , A61K2039/627
摘要： This invention relates to methods and kits for treating a subject having cancer, e.g. a patient, by administering to the subject an anticancer vaccine in combination with one or more checkpoint inhibitors.
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