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公开(公告)号:US20220169747A1
公开(公告)日:2022-06-02
申请号:US17442072
申请日:2020-03-20
发明人: Andrew Mark SCOTT , Hui Kong GAN , Zhanqi LIU , Sagun PARAKH
IPC分类号: C07K16/32 , G01N33/574
摘要: The present disclosure is directed to binding proteins to the extracellular domain (ECD) of HER2/ErbB2. More particularly, the binding proteins bind to a conformational epitope which is exposed in cells in response to HER2 amplification or activation.