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公开(公告)号:US11053227B2
公开(公告)日:2021-07-06
申请号:US16954704
申请日:2018-12-19
申请人: OLON S.P.A.
发明人: Corrado Colli , Giorgio Bertolini , Mara Sada , Faris Garis , Filippo Nisic , Aldo Bianchi , Cinzia Biaggi , Romano Di Fabio , Silvano Ronzoni , Stefania Bertuolo , Adolfo Prandi , Stefano Maiorana
IPC分类号: C07D405/06 , C07D207/408 , C12P13/02
摘要: Subject-matter of the present invention is a process for preparing intermediates for the synthesis of optically active beta-amino alcohols by enzymatic reduction of the corresponding beta-amino ketones. Subject-matter of the invention are also said novel synthesis intermediates and the use thereof in the preparation of active pharmaceutical ingredients, among which vilanterol and the salts thereof.