专利检索 ap:("ONO PHARMACEUTICAL CO.,LTD.") AND inv:"Melanie Janelle BEVILL" 第 1 页

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发明申请
SALT AND CRYSTAL FORM OF COMPOUND HAVING AGONISTIC ACTIVITY TO S1P5 RECEPTOR 有权

公开(公告)号：US20220289675A1

公开(公告)日：2022-09-15

申请号：US17634505

申请日：2020-08-19

申请人： ONO PHARMACEUTICAL CO.,LTD.

发明人： Shuhei OTANI , Takayuki FUJITO , Naoko IMURA , Hideomi KIJIMA , Stephan D. PARENT , Melanie Janelle BEVILL , Courtney S. JOHNSON , Travis Lee HOUSTON

IPC分类号： C07D205/04

摘要： An object of the present invention is to provide a compound with an improved balance of S1P5 receptor agonist activity with respect to S1P1 receptor, and a form suitable for drug substances of pharmaceuticals. Provided is Compound I having high S1P5 receptor-selective agonist activity on the S1P1 receptor. In addition, the crystal forms of Compound I, the salts of Compound I, and the crystal forms of salts thereof disclosed in the present invention are provided as drug substances of pharmaceuticals.