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公开(公告)号：US11180504B2
公开(公告)日：2021-11-23
申请号：US16083980
申请日：2017-03-15
发明人： Gopalan Balasubramanian , Maneesh Paul-Satyaseela , Chidambaram Venkateswaran Srinivasan , Sridhar Ramanathan Iyer , Hariharan Periasamy , Venkatesan Parameswaran , Bharani Thirunavukkarasu , Prabhakar Rao Gunturu , Manjula Devi Deshkumar , Venkateshwarlu Jakkala , Michael Miller , Ravi P. Nargund , Sheo Singh , Shuzhi Dong , Hongwu Wang , Katherine Young
IPC分类号： A61K31/407 , C07D487/04 , C07D519/00
摘要： This invention relates to carbapenem compounds of the following formula: wherein A, Z, X, R1, and R4 are as described herein, as well as stereoisomers, pharmaceutically acceptable salts or N-oxides thereof, which may be useful for the treatment of bacterial infections, particularly drug-resistant bacterial infections, as well as the processes for the preparation of compounds, the pharmaceutical compositions of these compounds and their use in the treatment of bacterial infection.
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公开(公告)号：US20200291029A1
公开(公告)日：2020-09-17
申请号：US16083980
申请日：2017-03-15
发明人： Gopalan Balasubramanian , Maneesh Paul-Satyaseela , Chidambaram Venkateswaran Srinivasan , Sridhar Ramanathan Iyer , Hariharan Periasamy , Venkatesan Parameswaran , Bharani Thirunavukkarasu , Prabhakar Rao Gunturu , Manjula Devi Deshkumar , Venkateshwarlu Jakkala , Michael Miller , Ravi P. Nargund , Sheo Singh , Shuzhi Dong , Hongwu Wang , Katherine Young
IPC分类号： C07D487/04 , C07D519/00
摘要： This invention relates to carbapenem compounds, their stereoisomers, pharmaceutically acceptable salts or N-oxides thereof, which may be useful for the treatment of bacterial infections, particularly drug-resistant bacterial infections, as well as the processes for the preparation of compounds, the pharmaceutical compositions of these compounds and their use in the treatment of bacterial infection.
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