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公开(公告)号：US20250035720A1
公开(公告)日：2025-01-30
申请号：US18684207
申请日：2022-08-22
Applicant: OSAKA UNIVERSITY
Inventor： Yoh Matsuki , Ken Kato , Toshimichi Fujiwara
Abstract: Provided are a polarizing agent that can selectively enhance NMR signals by the DNP-NMR method even in a reducing environment, and a method for selectively enhancing NMR signals. The present invention is a polarizing agent for use in the DNP-NMR method, the polarizing agent comprising nanodiamond particles, and the nanodiamond particles having a surface modified with a functional group capable of covalently binding to or interacting with proteins. The polarizing agent of the present invention can selectively enhance NMR signals by the DNP-NMR method even in a reducing environment.
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