公开(公告)号：US20240060878A1

公开(公告)日：2024-02-22

申请号：US18287336

申请日：2022-03-24

Applicant: OSAKA UNIVERSITY

Inventor： Susumu UCHIYAMA ,  Takahiro MARUNO ,  Tetsuo TORISU

IPC: G01N21/33 ,  G16B40/10

CPC classification number: G01N21/33 ,  G16B40/10

Abstract: An objection is to provide a method for characterizing a molecule delivery particle, the method comprising determining a molar concentration thereof.
The method for characterizing a molecule delivery particle, the method comprising subjecting a molecule delivery particle comprising a first particle and a second particle to particle separation with optical measurement to determine an increment in refractive index of each of the first particle and the second particle; and determining a molar concentration of each of the first particle and the second particle based on the increment in refractive index, a molecular weight, and a specific refractive index increment of each of the first particle and the second particle.

公开(公告)号：US20190284246A1

公开(公告)日：2019-09-19

申请号：US16097219

申请日：2017-04-25

Applicant: OSAKA UNIVERSITY ,  BIKENBIOMICS CO., LTD

Inventor： Shota NAKAMURA ,  Kazuki KAWAHARA ,  Hiroya OKI ,  Takuya YOSHIDA ,  Tadayasu OHKUBO ,  Yuji KOBAYASHI ,  Takahiro MARUNO ,  Daisuke MOTOOKA ,  Shigeaki MATSUDA ,  Toshio KODAMA ,  Tetsuya IIDA ,  Yasumitsu TSUJINO ,  Shunsuke FUKAKUSA

IPC: C07K14/245

Abstract: A peptide capable of preventing pathogenic bacteria from colonizing in digestive organs comprises a first domain having an amino acid sequence capable of binding to a minor pilin of IVb fimbriae, and a second domain having an amino acid sequence capable of multimerization, the second domain connect to the first domain via a linker sequence.