公开(公告)号：US20230193265A1

公开(公告)日：2023-06-22

申请号：US17925225

申请日：2021-05-12

Applicant: OSAKA UNIVERSITY

Inventor： Kazuhiko NAKATANI ,  Jun MATSUMOTO ,  Tatsumasa OKAMOTO ,  Chikara DOHNO ,  Asako SEIKE ,  Masayuki NAKAMORI

IPC: C12N15/113 ,  A61K31/496 ,  C07D401/04 ,  A61P21/00

CPC classification number: C12N15/113 ,  A61K31/496 ,  C07D401/04 ,  A61P21/00

Abstract: Provided is a novel agent capable of binding to a CUG repeat sequence. The agent comprises a compound A having a binding response of 10 resonance units (RU) or more at 25 nM to a (CUG)9 RNA immobilized at 401 RU as determined by surface plasmon resonance.