公开(公告)号：US20160121118A1

公开(公告)日：2016-05-05

申请号：US14920860

申请日：2015-10-22

Applicant: Oculeve, Inc.

Inventor： Manfred FRANKE ,  James Donald LOUDIN ,  John WARDLE ,  Mark Jeffrey HOLDBROOK

IPC: A61N1/36 ,  A61N1/372 ,  A61N1/375 ,  A61N1/05

CPC classification number: A61N1/36046 ,  A61N1/0526 ,  A61N1/0546 ,  A61N1/3606 ,  A61N1/36146 ,  A61N1/37205 ,  A61N1/37247 ,  A61N1/3756 ,  A61N1/3758

Abstract: Described herein are devices and methods of use thereof for treating dry eye, tired eye, or other forms of ocular discomfort such as from contact lenses. The methods generally include applying spatially and/or temporally patterned stimulation to one or more anatomical structures located in an ocular or nasal region. The electrical stimulation may elicit a reflex that activates the lacrimal gland or may directly activate the lacrimal gland or nerves innervating the lacrimal gland to produce tears. The devices may be implantable or handheld, and may be configured to deliver the spatially and/or temporally patterned stimulation patterns described.

Abstract translation: 本文描述了用于治疗干眼症，疲劳的眼睛或其它形式的眼部不适的装置和方法，例如由隐形眼镜。 方法通常包括将空间和/或时间图案化的刺激应用于位于眼睛或鼻部区域中的一个或多个解剖结构。 电刺激可以引起激活泪腺的反射，或者可以直接激活支配泪腺的泪腺或神经以产生泪液。 所述装置可以是可植入的或手持式的，并且可以被配置为递送所描述的空间和/或时间图案化的刺激图案。

公开(公告)号：US20170340884A1

公开(公告)日：2017-11-30

申请号：US15676910

申请日：2017-08-14

Applicant: Oculeve, Inc.

Inventor： Manfred FRANKE ,  James Donald LOUDIN ,  John WARDLE ,  Mark Jeffrey HOLDBROOK

IPC: A61N1/36 ,  A61N1/372 ,  A61N1/05 ,  A61N1/375

CPC classification number: A61N1/36046 ,  A61N1/0526 ,  A61N1/0546 ,  A61N1/3606 ,  A61N1/36146 ,  A61N1/37205 ,  A61N1/37247 ,  A61N1/3756 ,  A61N1/3758

Abstract: Described herein are devices and methods of use thereof for treating dry eye, tired eye, or other forms of ocular discomfort such as from contact lenses. The methods generally include applying spatially and/or temporally patterned stimulation to one or more anatomical structures located in an ocular or nasal region. The electrical stimulation may elicit a reflex that activates the lacrimal gland or may directly activate the lacrimal gland or nerves innervating the lacrimal gland to produce tears. The devices may be implantable or handheld, and may be configured to deliver the spatially and/or temporally patterned stimulation patterns described.