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公开(公告)号：US10112048B2
公开(公告)日：2018-10-30
申请号：US15676910
申请日：2017-08-14
申请人： Oculeve, Inc.
摘要： Described herein are devices and methods of use thereof for treating dry eye, tired eye, or other forms of ocular discomfort such as from contact lenses. The methods generally include applying spatially and/or temporally patterned stimulation to one or more anatomical structures located in an ocular or nasal region. The electrical stimulation may elicit a reflex that activates the lacrimal gland or may directly activate the lacrimal gland or nerves innervating the lacrimal gland to produce tears. The devices may be implantable or handheld, and may be configured to deliver the spatially and/or temporally patterned stimulation patterns described.
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公开(公告)号：US09737712B2
公开(公告)日：2017-08-22
申请号：US14920860
申请日：2015-10-22
申请人： Oculeve, Inc.
CPC分类号： A61N1/36046 , A61N1/0526 , A61N1/0546 , A61N1/3606 , A61N1/36146 , A61N1/37205 , A61N1/37247 , A61N1/3756 , A61N1/3758
摘要： Described herein are devices and methods of use thereof for treating dry eye, tired eye, or other forms of ocular discomfort such as from contact lenses. The methods generally include applying spatially and/or temporally patterned stimulation to one or more anatomical structures located in an ocular or nasal region. The electrical stimulation may elicit a reflex that activates the lacrimal gland or may directly activate the lacrimal gland or nerves innervating the lacrimal gland to produce tears. The devices may be implantable or handheld, and may be configured to deliver the spatially and/or temporally patterned stimulation patterns described.
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公开(公告)号：US20210031040A1
公开(公告)日：2021-02-04
申请号：US16995520
申请日：2020-08-17
申请人： Oculeve, Inc.
摘要： Described herein are devices and methods of use thereof for treating dry eye, tired eye, or other forms of ocular discomfort such as from contact lenses. The methods generally include applying spatially and/or temporally patterned stimulation to one or more anatomical structures located in an ocular or nasal region. The electrical stimulation may elicit a reflex that activates the lacrimal gland or may directly activate the lacrimal gland or nerves innervating the lacrimal gland to produce tears. The devices may be implantable or handheld, and may be configured to deliver the spatially and/or temporally patterned stimulation patterns described.
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公开(公告)号：US10780273B2
公开(公告)日：2020-09-22
申请号：US16137464
申请日：2018-09-20
申请人： Oculeve, Inc.
摘要： Described herein are devices and methods of use thereof for treating dry eye, tired eye, or other forms of ocular discomfort such as from contact lenses. The methods generally include applying spatially and/or temporally patterned stimulation to one or more anatomical structures located in an ocular or nasal region. The electrical stimulation may elicit a reflex that activates the lacrimal gland or may directly activate the lacrimal gland or nerves innervating the lacrimal gland to produce tears. The devices may be implantable or handheld, and may be configured to deliver the spatially and/or temporally patterned stimulation patterns described.
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公开(公告)号：US20190022392A1
公开(公告)日：2019-01-24
申请号：US16137464
申请日：2018-09-20
申请人： Oculeve, Inc.
摘要： Described herein are devices and methods of use thereof for treating dry eye, tired eye, or other forms of ocular discomfort such as from contact lenses. The methods generally include applying spatially and/or temporally patterned stimulation to one or more anatomical structures located in an ocular or nasal region. The electrical stimulation may elicit a reflex that activates the lacrimal gland or may directly activate the lacrimal gland or nerves innervating the lacrimal gland to produce tears. The devices may be implantable or handheld, and may be configured to deliver the spatially and/or temporally patterned stimulation patterns described.
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