公开(公告)号：US12227558B2

公开(公告)日：2025-02-18

申请号：US18167121

申请日：2023-02-10

Applicant: Ohio State Innovation Foundation

Inventor： Thomas J. Magliery ,  Mikhail M. Dikov ,  David Carbone ,  Nicholas Long ,  Brandon Sullivan ,  Elena Tchekneva

IPC: A61K38/00 ,  A61P35/00 ,  A61P37/06 ,  C07K14/705

Abstract: Described herein are Notch-modulating peptides (including monomers and multimers) capable of increasing or decreasing an immune response in a subject, compositions comprising the peptides, and methods of use thereof.

公开(公告)号：US11613567B2

公开(公告)日：2023-03-28

申请号：US16496163

申请日：2018-03-26

Applicant: Ohio State Innovation Foundation

Inventor： Thomas J. Magliery ,  Mikhail M. Dikov ,  David Carbone ,  Nicholas Long ,  Brandon Sullivan ,  Elena Tchekneva

IPC: A61K38/00 ,  C07K14/705 ,  A61P37/06 ,  A61P35/00

Abstract: Described herein are Notch-modulating peptides (including monomers and multimers) capable of increasing or decreasing an immune response in a subject, compositions comprising the peptides, and methods of use thereof.