专利检索 ap:("Omega Therapeutics, Inc.") AND inv:"Barbara Bennett" 第 1 页

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发明申请
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN B (APOB) GENE EXPRESSION 有权

公开(公告)号：US20220288237A1

公开(公告)日：2022-09-15

申请号：US17701325

申请日：2022-03-22

申请人： Omega Therapeutics, Inc.

发明人： Vishwesh Ashok Patil , Jeremiah D. Farelli , Rahul Karnik , Jesse Jerome Smith , Can Sarisozen , Adam Walter Scheidegger , Barbara Bennett

IPC分类号： A61K48/00 , C12N15/63 , A61K31/7115 , A61K9/127

摘要： The present invention provides agents and compositions for modulating expression (e.g., enhanced or reduced expression) of an apolipoprotein B (APOB) gene by targeting an APOB expression control region and methods of use thereof for treating an APOB associated disorder, e.g., hypercholesterolemia.