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公开(公告)号：US20090149533A1
公开(公告)日：2009-06-11
申请号：US11573237
申请日：2005-08-04
IPC分类号： A61K31/216 , C07C69/76 , A61P29/00
CPC分类号： A61K9/4875 , A61K9/4858 , A61K9/4866 , A61K31/192 , A61K47/44
摘要： The invention provides novel omega-3 ester-based oil solutions of fenofibrate. These solutions are substantially free of any food effect, effective in small volumes, and readily bioavailable. Notably, because the solutions of the invention contain an omega-3 ester-based oil as the major ingredient, they not only provide an antihyperlipidemic effect due to the fenofibrate active ingredient, they also provide recommended daily dosages of omega-3 oils (i.e., approximately 1 gram of omega-3 oil per day), or a portion thereof.
摘要翻译： 本发明提供了新的ω-3酯基非诺贝特油溶液。 这些溶液基本上没有任何食物效应，有效量小，且易于生物利用。 值得注意的是，由于本发明的溶液含有ω-3酯基油作为主要成分，它们不仅由于非诺贝特活性成分而提供抗高脂血症作用，而且还提供推荐的每日剂量的ω-3油（即， 每天约1克的ω-3油）或其一部分。
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公开(公告)号：US20090030077A1
公开(公告)日：2009-01-29
申请号：US12184864
申请日：2008-08-01
IPC分类号： A61K31/235 , C07C69/616 , A61P9/00 , A61P3/00
CPC分类号： A61K31/235
摘要： The invention provides novel omega-3 oil liquid formulations of fenofibrate. These formulations can be substantially free of any food effect, effective in small volumes, and readily bioavailable. Notably, because the formulations of the invention contain an omega-3 oil as the major ingredient, they not only provide anithypercholesterolemic and antihypertriglyceridemic effects due to the fenofibrate active ingredient, they also provide recommended daily dosages of omega-3 oils (i.e., approximately 1 gram of omega-3 oil per day), or a portion thereof.
摘要翻译： 本发明提供了非诺贝特的新型ω-3油液制剂。 这些制剂基本上不含任何食物效果，有效量小，易生物利用。 值得注意的是，由于本发明的制剂含有ω-3油作为主要成分，它们不仅由于非诺贝特活性成分而提供了高胆固醇血症和抗高血脂素胆固醇的作用，而且还提供了推荐的每日剂量的ω-3油（即约1 克每天的ω-3油）或其一部分。
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