公开(公告)号：US20190248767A1

公开(公告)日：2019-08-15

申请号：US16265012

申请日：2019-02-01

Applicant: PFIZER INC.

Inventor： Simon PLANKEN ,  Hengmiao CHENG ,  Michael Raymond COLLINS ,  Jillian Elyse SPANGLER ,  Alexei BROOUN ,  Andreas MADERNA ,  Cynthia PALMER ,  Maria Angelica LINTON ,  Asako NAGATA ,  Ping CHEN

IPC: C07D403/14 ,  C07D487/10 ,  A61P35/00

Abstract: Compounds of the general formula: processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

公开(公告)号：US20240336631A1

公开(公告)日：2024-10-10

申请号：US18625795

申请日：2024-04-03

Applicant: PFIZER INC.

Inventor： Benjamin Joseph BURKE ,  Alexander BURTEA ,  Jacob Cole DEFOREST ,  Asako NAGATA ,  Simon Paul PLANKEN ,  Jillian Elyse SPANGLER ,  Scott Channing SUTTON ,  Hanna Maria WISNIEWSKA ,  Shouliang YANG

IPC: C07D519/00 ,  A61K31/553 ,  A61P35/00

CPC classification number: C07D519/00 ,  A61K31/553 ,  A61P35/00

Abstract: The invention relates to compounds of Formula (I)-(III) and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The compounds the present invention may be useful in the treatment, prevention, suppression and amelioration diseases, disorders and conditions such as cancers.

公开(公告)号：US20190233440A1

公开(公告)日：2019-08-01

申请号：US16263185

申请日：2019-01-31

Applicant: PFIZER INC.

Inventor： Simon PLANKEN ,  Hengmiao CHENG ,  Michael Raymond COLLINS ,  Jillian Elyse SPANGLER ,  Alexei BROOUN ,  Andreas MADERNA ,  Cynthia PALMER ,  Maria Angelica LINTON ,  Asako NAGATA ,  Ping CHEN

IPC: C07D519/00 ,  C07D471/04 ,  C07D403/14 ,  C07D487/10 ,  C07D487/04 ,  C07D417/14 ,  A61P35/00

Abstract: Compounds of the general formula: processes for the preparation of these compounds, compositions containing these compounds, and the uses of these compounds.

公开(公告)号：US20250034173A1

公开(公告)日：2025-01-30

申请号：US18903345

申请日：2024-10-01

Applicant: PFIZER INC.

Inventor： Benjamin Joseph BURKE ,  Alexander BURTEA ,  Jacob Cole DEFOREST ,  Asako NAGATA ,  Simon Paul PLANKEN ,  Jillian Elyse SPANGLER ,  Scott Channing SUTTON ,  Hanna Maria WISNIEWSKA ,  Shouliang YANG

IPC: C07D519/00 ,  A61K31/553 ,  A61P35/00

Abstract: The invention relates to compounds of Formula (I)-(III) and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The compounds the present invention may be useful in the treatment, prevention, suppression and amelioration diseases, disorders and conditions such as cancers.