公开(公告)号：US20240294506A1

公开(公告)日：2024-09-05

申请号：US18346933

申请日：2023-07-05

Applicant: PFIZER INC.

Inventor： Douglas Carl BEHENNA ,  Kevin Daniel FREEMAN-COOK ,  Robert Louis HOFFMAN ,  Asako NAGATA ,  Sacha NINKOVIC ,  Scott Channing SUTTON

IPC: C07D403/12 ,  A61P35/00 ,  C07D413/12

CPC classification number: C07D403/12 ,  A61P35/00 ,  C07D413/12 ,  C07B2200/07

Abstract: This invention relates to compounds of Formula (I)






and enantiomers thereof, and to pharmaceutically acceptable salts of Formula (I) and said enantiomers, wherein R1, R2 and R3 are as defined herein. The invention further relates to pharmaceutical compositions comprising such compounds and salts, and to methods and uses of such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject in need thereof.