公开(公告)号：US20210353727A1

公开(公告)日：2021-11-18

申请号：US17336410

申请日：2021-06-02

Applicant: PHAIM PHARMA LTD

Inventor： TIHAMER ORBAN ,  JALAHEJ HEYMAN ,  NARA DAUBENEY ,  PIERS DAUBENEY

IPC: A61K39/00 ,  C07K14/62 ,  A61K38/28 ,  C07K14/47 ,  G01N33/68 ,  A61K45/06 ,  C07K14/00

Abstract: A composition for treating type 1 diabetes mellitus autoimmunity can include a therapeutically effective amount of two or more overlapping fragments of preproinsulin and a pharmaceutically acceptable carrier, wherein at least of the polypeptide fragments is antigenic.