公开(公告)号：US11242535B2

公开(公告)日：2022-02-08

申请号：US16429846

申请日：2019-06-03

申请人： PIONEER HI-BRED INTERNATIONAL, INC. ,  E. I. DU PONT DE NEMOURS AND COMPANY

发明人： Scott Diehn ,  Ajit Nott ,  David A Selinger ,  Carl Simmons ,  Priyanka Bhyri ,  Venkata S Tavva

IPC分类号： C12N15/82

摘要： The invention relates to gene expression regulatory sequences, specifically introns that act as enhancers of gene expression, the promoter and terminator sequences endogenously associated with these introns. Presence of these intronic enhancer sequences in proximity to promoter sequences leads to enhancement of gene expression. Methods of finding such new intronic enhancer sequences and using them to generate transgenic plants are also described.

公开(公告)号：US10344290B2

公开(公告)日：2019-07-09

申请号：US15660390

申请日：2017-07-26

申请人： PIONEER HI-BRED INTERNATIONAL, INC. ,  E I DU PONT DE NEMOURS AND COMPANY

发明人： Scott Diehen ,  Ajit Nott ,  David A. Selinger ,  Carl Simmons ,  Priyanka Bhyri ,  Venkata S. Tavva

IPC分类号： C12N15/82

摘要： The invention relates to gene expression regulatory sequences, specifically introns that act as enhancers of gene expression, the promoter and terminator sequences endogenously associated with these introns. Presence of these intronic enhancer sequences in proximity to promoter sequences leads to enhancement of gene expression. Methods of finding such new intronic enhancer sequences and using them to generate transgenic plants are also described.

公开(公告)号：US11248233B2

公开(公告)日：2022-02-15

申请号：US16032228

申请日：2018-07-11

申请人： E. I. DU PONT DE NEMOURS AND COMPANY

发明人： Priyanka Bhyri ,  Nandini Krishnamurthy ,  Eswar Narayanan ,  Ajit Nott ,  Rinku Ranjan Sarangi

IPC分类号： C12N15/82

摘要： This invention relates to gene expression regulatory sequences, specifically transcription terminator sequences. Plant transcription terminator sequences are described herein. Methods for identifying novel plant transcription terminator sequences that can terminate transcription in one orientation or in a bidirectional manner and methods of using these terminator sequences to generate transgenic plants are described herein.

公开(公告)号：US20180312857A1

公开(公告)日：2018-11-01

申请号：US16032228

申请日：2018-07-11

申请人： E. I. DU PONT DE NEMOURS AND COMPANY

发明人： Priyanka Bhyri ,  Nandini Krishnamurthy ,  Eswar Narayanan ,  Ajit Nott ,  Rinku Ranjan Sarangi

IPC分类号： C12N15/82

CPC分类号： C12N15/8216 ,  C12N15/8222

摘要： This invention relates to gene expression regulatory sequences, specifically transcription terminator sequences. Plant transcription terminator sequences are described herein. Methods for identifying novel plant transcription terminator sequences that can terminate transcription in one orientation or in a bidirectional manner and methods of using these terminator sequences to generate transgenic plants are described herein.