公开(公告)号：US20210262014A1

公开(公告)日：2021-08-26

申请号：US16803731

申请日：2020-02-27

Applicant: POSTECH Research and Business Development Foundation

Inventor： Hyun-Suk LIM ,  Kang Ju LEE

IPC: C12Q1/6825 ,  C12Q1/686 ,  C12Q1/6869 ,  C12Q1/6876

Abstract: Disclosed are a nanostructure including a nanoparticle, and a first compound including a probe and bound to the surface of the nanoparticle, a second compound including a DNA sequence encoding the probe and bound to the surface of the nanoparticle, and optionally substituted or unsubstituted polyalkylene glycol bound to the surface of the nanoparticle, wherein when the nanostructure does not include substituted or unsubstituted polyalkylene glycol bound to the surface of the nanoparticle, a ratio ((n1+n2)/w) of the sum of the number of moles (n1) of the first compound and the number of moles (n2) of the second compound relative to the weight (w) of the nanostructure is about 1.2 nmol/g to about 85 μmol/g on average, a biosensor including the nanostructure, and a method of screening a biological material using the nanostructure or the biosensor.