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公开(公告)号:US20200262835A1
公开(公告)日:2020-08-20
申请号:US16784320
申请日:2020-02-07
申请人: PROXIMAGEN, LLC
发明人: Max ESPENSEN , Lee PATIENT , David EVANS , Edward SAVORY , Iain SIMPSON
IPC分类号: C07D471/04 , A61K31/40 , A61K31/4745 , A61K31/495 , A61K31/501 , A61K31/506 , C07C53/18
摘要: Compound of formula (I) or a pharmaceutically acceptable salt, or N-oxide thereof, that are inhibitors of SSAO activity: where V, W, X, Y, Z, R1, and R3 are as defined herein.
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公开(公告)号:US20200002335A1
公开(公告)日:2020-01-02
申请号:US16542792
申请日:2019-08-16
申请人: PROXIMAGEN, LLC
发明人: Max ESPENSEN , Lee PATIENT , David EVANS , Iain SIMPSON , Edward SAVORY
IPC分类号: C07D471/04 , A61K31/40 , C07C53/18
摘要: The compounds of formula (I) are inhibitors of SSAO activity wherein V, W, X, Y, Z, R1 and R2 are as defined in the claims.
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公开(公告)号:US20200347059A1
公开(公告)日:2020-11-05
申请号:US16933417
申请日:2020-07-20
申请人: PROXIMAGEN, LLC
发明人: Max ESPENSEN , Lee PATIENT , David EVANS , Iain SIMPSON , Edward SAVORY
IPC分类号: C07D471/04 , A61K31/40 , A61K31/4745 , A61K31/495 , A61K31/501 , A61K31/506 , C07C53/18
摘要: A process for the preparation of a compound of formula (Ia) or a pharmaceutically acceptable salt, or N-oxide thereof that includes reacting a compound of formula (IIIa) or (Va) with a compound of formula (IX) to form the compound of formula (Ia)
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