公开(公告)号：US20220265811A1

公开(公告)日：2022-08-25

申请号：US17754280

申请日：2020-07-14

申请人： PULIKE BIOLOGICAL ENGINEERING, INC.

发明人： Kegong Tian ,  Mengyue Wang ,  Wujie Liu ,  Xuke Zhang

IPC分类号： A61K39/145 ,  A61K39/17 ,  A61K39/215 ,  A61K39/235 ,  A61K39/39 ,  A61P31/20

摘要： The present disclosure provides a tFiber protein fragment of avian egg drop syndrome virus, wherein the gene that encoded the tFiber protein fragment of avian egg drop syndrome virus has a nucleotide sequence shown in SEQ ID NO. 2 or a degenerate sequence thereof, and a vaccine composition prepared from the protein fragment. The fragment has good immunogenicity and is capable of preparing combined vaccine with various antigens, producing complete protection to the chickens and ducks.