公开(公告)号：US20210220043A1

公开(公告)日：2021-07-22

申请号：US17152665

申请日：2021-01-19

申请人： Pajhand IRANITALAB ,  Casey Andrew MILLER ,  Thomas Ryan McGRATH ,  Manuel Arzadon JAVIER, JR. ,  Anisha BAPNA ,  Zoar Jacob ENGELMAN ,  Howard LEVIN ,  Nicholas C. VanDILLEN ,  Anne Marie AHONEN

发明人： Pajhand IRANITALAB ,  Casey Andrew MILLER ,  Thomas Ryan McGRATH ,  Manuel Arzadon JAVIER, JR. ,  Anisha BAPNA ,  Zoar Jacob ENGELMAN ,  Howard LEVIN ,  Nicholas C. VanDILLEN ,  Anne Marie AHONEN

IPC分类号： A61B18/14

摘要： Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.

公开(公告)号：US20210298824A1

公开(公告)日：2021-09-30

申请号：US17304007

申请日：2021-06-11

申请人： Pajhand IRANITALAB ,  Casey Andrew MILLER ,  Thomas Ryan McGRATH ,  Manuel Arzadon JAVIER ,  Anisha BAPNA ,  Zoar Jacob ENGELMAN ,  Howard LEVIN ,  Nicholas C. VanDILLEN ,  Anne Marie AHONEN

发明人： Pajhand IRANITALAB ,  Casey Andrew MILLER ,  Thomas Ryan McGRATH ,  Manuel Arzadon JAVIER ,  Anisha BAPNA ,  Zoar Jacob ENGELMAN ,  Howard LEVIN ,  Nicholas C. VanDILLEN ,  Anne Marie AHONEN

IPC分类号： A61B18/14

摘要： Systems, devices, and methods for transvascular ablation of target tissue. The devices and methods may, in some examples, be used for splanchnic nerve ablation to increase splanchnic venous blood capacitance to treat at least one of heart failure and hypertension. For example, the devices disclosed herein may be advanced endovascularly to a target vessel in the region of a thoracic splanchnic nerve (TSN), such as a greater splanchnic nerve (GSN) or a TSN nerve root. Also disclosed are methods of treating heart failure, such as HFpEF, by endovascularly ablating a thoracic splanchnic nerve to increase venous capacitance and reduce pulmonary blood pressure.