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公开(公告)号：US20220144872A1
公开(公告)日：2022-05-12
申请号：US17350267
申请日：2021-06-17
IPC分类号： C07F15/02 , C07C51/41 , A61K33/26 , A61K31/295 , C07C59/265
摘要： The present invention discloses pharmaceutical-grade ferric organic compounds, including ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. A manufacturing and quality control process for making a pharmaceutical-grade ferric citrate that consistently complies with the established Manufacture Release Specification is also disclosed. The pharmaceutical-grade ferric organic compounds are suitable for treating disorders characterized by elevated serum phosphate levels.
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2.发明申请公开(公告)号：US20190269722A1
公开(公告)日：2019-09-05
申请号：US16352455
申请日：2019-03-13
IPC分类号： A61K33/26 , C07C59/265 , A61K31/295 , C07C51/41
摘要： The present invention discloses pharmaceutical-grade ferric organic compounds, including ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. A manufacturing and quality control process for making a pharmaceutical-grade ferric citrate that consistently complies with the established Manufacture Release Specification is also disclosed. The pharmaceutical-grade ferric organic compounds are suitable for treating disorders characterized by elevated serum phosphate levels.
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公开(公告)号：US20220213133A1
公开(公告)日：2022-07-07
申请号：US17405543
申请日：2021-08-18
IPC分类号： C07F15/02 , C07C51/41 , A61K33/26 , A61K31/295 , C07C59/265
摘要： The present invention discloses a novel form of ferric organic compounds, including a form of ferric citrate, which are soluble over a wider range of pH, and which have a large active surface area. The ferric organic compounds of the present invention can be delivered effectively by oral route with better delivery to treat patients suffering from hyperphosphatemia, metabolic acidosis and other disorders responsive to ferric organic compound therapy.
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