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公开(公告)号:US5698521A
公开(公告)日:1997-12-16
申请号:US416602
申请日:1995-04-04
申请人: Patricia A. McKernan , Lennie Chen , Charles Petrie , James Piggott , Robert R. West , Shirley Gasper , Colin Lellis
发明人: Patricia A. McKernan , Lennie Chen , Charles Petrie , James Piggott , Robert R. West , Shirley Gasper , Colin Lellis
IPC分类号: A61K38/00 , C07K14/575 , C07K5/00 , C07K7/00
CPC分类号: C07K14/57527 , A61K38/00
摘要: The invention provides isolated, biologically active native calcitonin mimetics and related methods. These small 16 and 17 amino acid proteins mimic the interaction of calcitonin on its receptor, and also exhibit bone resorptive inhibiting activity.
摘要翻译: 本发明提供了分离的,生物活性的天然降钙素模拟物和相关方法。 这些小的16和17氨基酸蛋白质模拟降钙素对其受体的相互作用,并且还表现出骨吸收抑制活性。