-
公开(公告)号:US06129487A
公开(公告)日:2000-10-10
申请号:US127026
申请日:1998-07-30
CPC分类号: E02D7/12 , B63B21/28 , E02D2250/0061 , Y10S173/01
摘要: A tool is provided for use in submerged condition for installing anchor or foundation elements such as piles in a ground formation that is submerged under a body of water. A hammer body is fixedly supported in axial alignment with the head of a pile that is to be driven and carries a reaction body guided for movement thereon in a direction that is axial to the pile. The hammer body and reaction body define opposed first and second ends of an expansion chamber. A pyrotechnic charge is initiated to create a rapidly expanding volume of high pressure gas in the expansion chamber to generate a downwards pressure force pulse to drive the pile, an equal and opposite upwards pressure force pulse being applied to the reaction body. Damping structure operatively associated with the reaction body interacts with the water in which the tool is submerged using the inertia of the water to resist upwards movement of reaction body.
摘要翻译: 提供了一种用于淹没条件的工具,用于将锚固件或基础元件(例如桩)沉积在淹没在水体下面的地层中。 锤体与被驱动的桩的头部轴向对准地固定,并且承载引导其的反作用体沿着与桩轴向的方向移动。 锤体和反作用体限定了膨胀室的相对的第一和第二端。 启动烟火装料以在膨胀室中产生快速膨胀的高压气体体积,以产生向下的压力脉冲来驱动桩,施加到反应体上的相等且相反的向上的压力脉冲。 与反应体可操作地相关联的阻尼结构与工具被浸没的水相互作用,使用水的惯性来抵抗反应体的向上运动。
-
公开(公告)号:US20110224223A1
公开(公告)日:2011-09-15
申请号:US13003562
申请日:2009-07-08
申请人: Kevan M. Shokat , David Fruman , Pingda Ren , Troy Edward Wilson , Liansheng Li , Andrew Hsieh , Morris Feldman , Beth Apsel , Yi Liu , Christian Rommel , Katrina Chan , Davide Ruggero , David Pearce , Matthew Janes
发明人: Kevan M. Shokat , David Fruman , Pingda Ren , Troy Edward Wilson , Liansheng Li , Andrew Hsieh , Morris Feldman , Beth Apsel , Yi Liu , Christian Rommel , Katrina Chan , Davide Ruggero , David Pearce , Matthew Janes
IPC分类号: A61K31/506 , C12N5/09 , C12N9/99 , A61K31/519 , A61K31/436 , A61P35/00 , A61P13/12 , A61P9/12 , A61P9/04 , A61P1/16
CPC分类号: A61K31/519 , C12Q1/485 , G01N2500/04 , G01N2510/00
摘要: The present invention provides methods and compositions for selective modulation of certain protein kinases, and especially mTor complexes. The methods and compositions are particularly useful in inhibiting mTor selectively for therapeutic applications.
摘要翻译: 本发明提供了选择性调节某些蛋白激酶,特别是mTor复合物的方法和组合物。 所述方法和组合物特别可用于抑制mTor用于治疗应用。
-