公开(公告)号：US20170252391A1

公开(公告)日：2017-09-07

申请号：US15524757

申请日：2015-02-11

Applicant: PAWAN KUMAR GOEL

Inventor： Ashok SHARMA ,  Kiran TEWARI

IPC: A61K36/48 ,  A61K9/48 ,  A61K31/7048 ,  A61K9/00

CPC classification number: A61K36/48 ,  A61K9/0053 ,  A61K9/48 ,  A61K31/7048

Abstract: Discloses is a single herb extract for the treatment of PCOS (Poly Cystic Ovarian Syndrome) when given in oral dosage form as capsules of 500 mg, twice a day for period of time ranging from 30-90 days, The extract is obtained from fenugreek seeds using a specific method of extraction and comprises five furostanolicsaponins present in synergistic ratios as in Table 1 and having analytical profile as in FIG. 1.

公开(公告)号：US20210093686A1

公开(公告)日：2021-04-01

申请号：US17007180

申请日：2020-08-31

Applicant: PAWAN KUMAR GOEL

Inventor： Ashok SHARMA ,  Kiran TEWARI

IPC: A61K36/48 ,  A61K9/00 ,  A61K9/48 ,  A61K31/7048

Abstract: Discloses is a single herb extract for the treatment of PCOS (Poly Cystic Ovarian Syndrome) when given in oral dosage form as capsules of 500 mg, twice a day for period of time ranging from 30-90 days. The extract is obtained from fenugreek seeds using a specific method of extraction and comprises five furostanolicsaponins present in synergistic ratios as in Table 1 and having analytical profile as in FIG. 1.

公开(公告)号：US20190330203A1

公开(公告)日：2019-10-31

申请号：US16406422

申请日：2019-05-08

Applicant: Pawan Kumar GOEL

Inventor： Kiran TEWARI ,  Ashok SHARMA

IPC: C07D459/00 ,  B01D11/02

Abstract: Present invention discloses a novel, commercially viable process for extraction of Alpha yohimbine from the bark, stem and leaves of Rauwolfia species. The extract is obtained by a precipitation method involving alternate steps of acidification and alkalization along with use of specific organic solvents. The extract gives higher yield of 7-8 fold as compared to other processes and without use of any column chromatography at all. Yield of alpha yohimbine from roots and leaves of Rauwolfia canescens by process of present invention was 0.017% and 0.4% respectively, indicating that leaves are a much better source. The HPLC analysis of the compound obtained indicated a purity of >90%.