专利检索 ap:("Peiming ZHANG" OR "Sovan BISWAS" OR "Suman SEN" OR "Stuart LINDSAY") AND inv:"Sovan BISWAS" 第 1 页

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发明申请
NON-HYDROGEN-BONDING UNIVERSAL READER FOR DNA SEQUENCING 审中-公开

公开(公告)号：US20190195856A1

公开(公告)日：2019-06-27

申请号：US16327232

申请日：2017-08-21

申请人： Peiming ZHANG , Sovan BISWAS , Suman SEN , Stuart LINDSAY

发明人： Peiming ZHANG , Sovan BISWAS , Suman SEN , Stuart LINDSAY

IPC分类号： G01N33/487 , C07C321/10 , C12Q1/6869

CPC分类号： G01N33/48721 , C07C321/10 , C07C2603/50 , C12Q1/6869 , C12Q2563/116 , C12Q2563/157 , C12Q2565/607

摘要： The present disclosure provides apparatus and methods for determining the sequence of a nucleic acid. The apparatus comprises electrodes that form a tunnel gap through which the nucleic acid can pass. The electrodes comprise a reagent that is capable of selectively interacting with a nucleobase of the nucleic acid sequence. When the reagent interacts with a nucleobase, a detectable signal is produced and used to identify the nucleobase of the nucleic acid. Advantageously, the apparatus of this disclosure is specific to identifying nucleic acids.