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公开(公告)号:US06720327B2
公开(公告)日:2004-04-13
申请号:US09963926
申请日:2001-09-26
申请人: Peter Ruminski , Thomas D. Penning , Lan Jiang , Balekudru Devadas , Thomas Rogers , Jennifer VanCamp , Chester Yuan
发明人: Peter Ruminski , Thomas D. Penning , Lan Jiang , Balekudru Devadas , Thomas Rogers , Jennifer VanCamp , Chester Yuan
IPC分类号: A61K31505
CPC分类号: C07D405/12 , C07D309/30 , C07D405/14
摘要: The present invention relates to a class of compounds represented by the Formula I. or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the &agr;v&bgr;3 and/or the &agr;v&bgr;5 integrin.
摘要翻译: 本发明涉及一类由式I表示的化合物或其药学上可接受的盐,包含式I化合物的药物组合物,以及选择性抑制或拮抗阿尔法博乙和/或阿尔法肽5整联蛋白的方法。
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公开(公告)号:US06906051B2
公开(公告)日:2005-06-14
申请号:US10717238
申请日:2003-11-19
申请人: Peter Ruminiski , Thomas D. Penning , Lan Jiang , Balekudru Devadas , Thomas Rogers , Jennifer VanCamp , Chester Yuan
发明人: Peter Ruminiski , Thomas D. Penning , Lan Jiang , Balekudru Devadas , Thomas Rogers , Jennifer VanCamp , Chester Yuan
IPC分类号: C07D307/33 , A61K31/365 , A61K31/506 , A61P1/02 , A61P3/14 , A61P9/00 , A61P9/10 , A61P19/02 , A61P19/10 , A61P21/00 , A61P27/02 , A61P31/12 , A61P35/00 , A61P35/04 , A61P43/00 , C07D309/30 , C07D405/12 , C07D405/14 , A61K31/33 , A61K31/505 , C07D239/00 , C07D305/00 , C07D407/00
CPC分类号: C07D405/12 , C07D309/30 , C07D405/14
摘要: The present invention relates to a class of compounds represented by the Formula I: or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of the Formula I, and methods of selectively inhibiting or antagonizing the αVβ3 and/or the αVβ5 integrin.
摘要翻译: 本发明涉及一类由式I表示的化合物或其药学上可接受的盐,包含式I化合物的药物组合物,以及选择性抑制或拮抗α SUB> 3和/或α5AT55整联蛋白。
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