公开(公告)号：US20120049847A1

公开(公告)日：2012-03-01

申请号：US13075087

申请日：2011-03-29

申请人： Peter Vaes ,  Stephanie Teughels

发明人： Peter Vaes ,  Stephanie Teughels

IPC分类号： G01R33/00

CPC分类号： G01N24/10 ,  G01R33/281 ,  G01R33/60

摘要： A method and system for performing pulsed electron paramagnetic resonance is disclosed. In one aspect, the method includes generating an excitation pulse train for applying to an object having probes and detecting from the probes an echo response induced by the excitation pulse train.

摘要翻译： 公开了一种用于执行脉冲电子顺磁共振的方法和系统。 一方面，该方法包括产生用于向具有探针的物体施加的激励脉冲串，并且从探测器检测由激励脉冲序列引起的回波响应。

公开(公告)号：US08542014B2

公开(公告)日：2013-09-24

申请号：US13617502

申请日：2012-09-14

申请人： Stephanie Teughels ,  Peter Vaes

发明人： Stephanie Teughels ,  Peter Vaes

IPC分类号： G01V3/00

CPC分类号： G01N24/10 ,  B82Y15/00 ,  B82Y25/00 ,  G01R33/281 ,  G01R33/445 ,  G01R33/5601 ,  G01R33/60

摘要： A method and system are disclosed for gathering information about an object including single domain particles which have a diameter in the range of about 5 to 80 nm. In one aspect, a method includes generating a static magnetic field of less than about 0.1 Tesla on the object and generating an RF energy, pulsed or continuous wave, so as to generate electron paramagnetic resonance of the single domain particles. The method also includes detecting the electron paramagnetic resonance of the single domain particles in the form of an image of the object. The single domain particles may have a predetermined diameter and a predetermined saturation magnetization and the applied magnetic field may be such that the single domain particles reach a magnetization being at least about 10% of the saturation magnetization. The method may be used for detecting tags in an object and for activating tags.

摘要翻译： 公开了一种用于收集关于包括直径在约5至80nm范围内的单畴粒子的物体的信息的方法和系统。 在一个方面，一种方法包括在物体上产生小于约0.1特斯拉的静态磁场，并产生RF能量，脉冲或连续波，以便产生单畴粒子的电子顺磁共振。 该方法还包括以对象的图像的形式检测单畴粒子的电子顺磁共振。 单畴粒子可以具有预定的直径和预定的饱和磁化强度，并且所施加的磁场可以使得单结构域粒子达到至少约饱和磁化强度的约10％的磁化强度。 该方法可以用于检测对象中的标签和激活标签。

公开(公告)号：US09551773B2

公开(公告)日：2017-01-24

申请号：US14006153

申请日：2012-03-21

申请人： Peter Vaes ,  Stephanie Teughels

发明人： Peter Vaes ,  Stephanie Teughels

IPC分类号： G01V3/00 ,  G01R33/60 ,  G01N24/10

CPC分类号： G01R33/60 ,  G01N24/10

摘要： A system and method involve performing electron paramagnetic resonance on an object under study. The system comprises a first field generator adapted for generating an orienting magnetic field for orienting the magnetization of the object under study and a second field generator adapted for generating RF excitation waves at a frequency to generate electron paramagnetic resonance (EPR) in the object under test. The system also comprises a detection unit adapted for detecting the EPR signals emitted by the object under test and a control unit adapted for controlling the relative orientation of the orienting magnetic field induced by the first field generator with respect to the detection unit. The system furthermore comprises a processing unit programmed for combining detected EPR signals obtained using different relative orientations of the orienting magnetic field with respect to the detection unit.

摘要翻译： 一种系统和方法涉及在正在研究的物体上进行电子顺磁共振。 该系统包括第一场发生器，其适于产生用于定向被研究物体的磁化的定向磁场和适于产生频率上的RF激发波的第二场发生器，以在被测物体中产生电子顺磁共振（EPR） 。 该系统还包括一个检测单元，用于检测被测物体发出的EPR信号，以及一个控制单元，用于控制由第一场发生器相对于检测单元感应的定向磁场的相对取向。 该系统还包括处理单元，其被编程用于组合使用定向磁场的不同相对取向获得的相对于检测单元的检测到的EPR信号。

公开(公告)号：US08816685B2

公开(公告)日：2014-08-26

申请号：US13075087

申请日：2011-03-29

申请人： Peter Vaes ,  Stephanie Teughels

发明人： Peter Vaes ,  Stephanie Teughels

IPC分类号： G01V3/00

CPC分类号： G01N24/10 ,  G01R33/281 ,  G01R33/60

摘要： A method and system for performing pulsed electron paramagnetic resonance is disclosed. In one aspect, the method includes generating an excitation pulse train for applying to an object having probes and detecting from the probes an echo response induced by the excitation pulse train.

摘要翻译： 公开了一种用于执行脉冲电子顺磁共振的方法和系统。 一方面，该方法包括产生用于向具有探针的物体施加的激励脉冲串，并且从探测器检测由激励脉冲序列引起的回波响应。

公开(公告)号：US20140009159A1

公开(公告)日：2014-01-09

申请号：US14006153

申请日：2012-03-21

申请人： Peter Vaes ,  Stephanie Teughels

发明人： Peter Vaes ,  Stephanie Teughels

IPC分类号： G01R33/60

CPC分类号： G01R33/60 ,  G01N24/10

摘要： A system and method involve performing electron paramagnetic resonance on an object under study. The system comprises a first field generator adapted for generating an orienting magnetic field for orienting the magnetization of the object under study and a second field generator adapted for generating RF excitation waves at a frequency to generate electron paramagnetic resonance (EPR) in the object under test. The system also comprises a detection unit adapted for detecting the EPR signals emitted by the object under test and a control unit adapted for controlling the relative orientation of the orienting magnetic field induced by the first field generator with respect to the detection unit. The system furthermore comprises a processing unit programmed for combining detected EPR signals obtained using different relative orientations of the orienting magnetic field with respect to the detection unit.

摘要翻译： 一种系统和方法涉及在正在研究的物体上进行电子顺磁共振。 该系统包括第一场发生器，其适于产生用于定向被研究物体的磁化的定向磁场和适于产生频率上的RF激发波的第二场发生器，以在被测物体中产生电子顺磁共振（EPR） 。 该系统还包括一个检测单元，用于检测被测物体发出的EPR信号，以及一个控制单元，用于控制由第一场发生器相对于检测单元感应的定向磁场的相对取向。 该系统还包括处理单元，其被编程用于组合使用定向磁场的不同相对取向获得的相对于检测单元的检测到的EPR信号。

公开(公告)号：US08283926B2

公开(公告)日：2012-10-09

申请号：US12959310

申请日：2010-12-02

申请人： Stephanie Teughels ,  Peter Vaes

发明人： Stephanie Teughels ,  Peter Vaes

IPC分类号： G01V3/00

CPC分类号： G01N24/10 ,  B82Y15/00 ,  B82Y25/00 ,  G01R33/281 ,  G01R33/445 ,  G01R33/5601 ,  G01R33/60

摘要： A method and system are disclosed for gathering information about an object including single domain particles which have a diameter in the range of about 5 to 80 nm. In one aspect, a method includes generating a static magnetic field of less than about 0.1 Tesla on the object and generating an RF energy, pulsed or continuous wave, so as to generate electron paramagnetic resonance of the single domain particles. The method also includes detecting the electron paramagnetic resonance of the single domain particles in the form of an image of the object. The single domain particles may have a predetermined diameter and a predetermined saturation magnetization and the applied magnetic field may be such that the single domain particles reach a magnetization being at least about 10% of the saturation magnetization. The method may be used for detecting tags in an object and for activating tags.

摘要翻译： 公开了一种用于收集关于包括直径在约5至80nm范围内的单畴粒子的物体的信息的方法和系统。 在一个方面，一种方法包括在物体上产生小于约0.1特斯拉的静态磁场，并产生RF能量，脉冲或连续波，以便产生单畴粒子的电子顺磁共振。 该方法还包括以对象的图像的形式检测单畴粒子的电子顺磁共振。 单畴粒子可以具有预定的直径和预定的饱和磁化强度，并且所施加的磁场可以使得单结构域粒子达到至少约饱和磁化强度的约10％的磁化强度。 该方法可以用于检测对象中的标签和激活标签。

公开(公告)号：US20110148414A1

公开(公告)日：2011-06-23

申请号：US12959310

申请日：2010-12-02

申请人： Stephanie Teughels ,  Peter Vaes

发明人： Stephanie Teughels ,  Peter Vaes

IPC分类号： G01R33/00

CPC分类号： G01N24/10 ,  B82Y15/00 ,  B82Y25/00 ,  G01R33/281 ,  G01R33/445 ,  G01R33/5601 ,  G01R33/60

摘要： A method and system are disclosed for gathering information about an object including single domain particles which have a diameter in the range of about 5 to 80 nm. In one aspect, a method includes generating a static magnetic field of less than about 0.1 Tesla on the object and generating an RF energy, pulsed or continuous wave, so as to generate electron paramagnetic resonance of the single domain particles. The method also includes detecting the electron paramagnetic resonance of the single domain particles in the form of an image of the object. The single domain particles may have a predetermined diameter and a predetermined saturation magnetization and the applied magnetic field may be such that the single domain particles reach a magnetization being at least about 10% of the saturation magnetization. The method may be used for detecting tags in an object and for activating tags.

摘要翻译： 公开了一种用于收集关于包括直径在约5至80nm范围内的单畴粒子的物体的信息的方法和系统。 在一个方面，一种方法包括在物体上产生小于约0.1特斯拉的静态磁场，并产生RF能量，脉冲或连续波，以便产生单畴粒子的电子顺磁共振。 该方法还包括以对象的图像的形式检测单畴粒子的电子顺磁共振。 单畴粒子可以具有预定的直径和预定的饱和磁化强度，并且所施加的磁场可以使得单结构域粒子达到至少约饱和磁化强度的约10％的磁化强度。 该方法可以用于检测对象中的标签和激活标签。