公开(公告)号：US20110124130A1

公开(公告)日：2011-05-26

申请号：US12936318

申请日：2008-04-03

申请人： Peter Wagner ,  Frank Zaugg ,  Mark Mitchnik

发明人： Peter Wagner ,  Frank Zaugg ,  Mark Mitchnik

IPC分类号： G01N33/543

CPC分类号： G01N33/558 ,  G01N33/54366

摘要： A system and method for determining the presence and/or concentration of one or more analytes in a sample that comprises a fluid, the system comprising a substrate comprising a sample inlet or inlets and one or more analyte determination flow paths, each analyte determination flow path comprising a defined beginning and a defined terminus and comprising at least one capture zone containing a capture agent for an analyte, the capture agent or agents being immobilized along a portion of the flow path or paths, the flow path or paths being designed so that the one or more analytes are depleted from the sample and bound to the portion of the flow path or paths containing immobilized capture agent or agents, producing an analyte depletion end region for each analyte between the beginning and the terminus of the analyte determination flow path.

摘要翻译： 一种用于确定样品中一种或多种分析物在含有流体的存在和/或浓度的系统和方法，所述系统包括含有样品入口或入口以及一个或多个分析物确定流路的基底，每个分析物确定流路 包括限定的起始点和限定的末端，并且包含至少一个含有分析物的捕获剂的捕获区，所述捕获剂或试剂沿所述流动路径或路径的一部分被固定，所述流路或路径被设计成使得 一个或多个分析物从样品中消耗并且结合到含有固定化捕获剂或试剂的流动路径或路径的部分，为分析物确定流路的开始和终点之间的每个分析物产生分析物耗尽端区。