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公开(公告)号：US20240140937A1
公开(公告)日：2024-05-02
申请号：US18520638
申请日：2023-11-28
申请人： Pfizer Inc.
发明人： Markus Boehm , Shawn Cabral , Matthew S. Dowling , Kentaro Futatsugi , Kim Huard , Esther Cheng Yin Lee , Allyn T. Londregan , Jana Polivkova , David A. Price , Qifang Li
IPC分类号： C07D405/14 , A61K31/506 , A61K45/06 , C07D401/14 , C07D409/14
CPC分类号： C07D405/14 , A61K31/506 , A61K45/06 , C07D401/14 , C07D409/14 , A61P3/06
摘要： Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
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公开(公告)号：US10071992B2
公开(公告)日：2018-09-11
申请号：US15674914
申请日：2017-08-11
申请人： Pfizer Inc.
发明人： Markus Boehm , Shawn Cabral , Matthew S. Dowling , Kentaro Futatsugi , Kim Huard , Esther Cheng Yin Lee , Allyn T. Londregan , Jana Polivkova , David A. Price , Qifang Li
IPC分类号： C07D401/00 , C07D253/08 , C07D401/04 , A61K9/14 , C07D405/14 , A61K31/506 , A61K45/06 , C07D409/14 , C07D401/14
摘要： Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
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公开(公告)号：US20180051012A1
公开(公告)日：2018-02-22
申请号：US15674914
申请日：2017-08-11
申请人： Pfizer Inc.
发明人： Markus Boehm , Shawn Cabral , Matthew S. Dowling , Kentaro Futatsugi , Kim Huard , Esther Cheng Yin Lee , Allyn T. Londregan , Jana Polivkova , David A. Price , Qifang Li
IPC分类号： C07D405/14 , A61K31/506 , A61K45/06 , C07D409/14
CPC分类号： C07D405/14 , A61K31/506 , A61K45/06 , C07B2200/13 , C07D401/14 , C07D409/14
摘要： Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
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公开(公告)号：US11034678B2
公开(公告)日：2021-06-15
申请号：US16793441
申请日：2020-02-18
申请人： Pfizer Inc.
发明人： Markus Boehm , Shawn Cabral , Matthew S. Dowling , Kentaro Futatsugi , Kim Huard , Esther Cheng Yin Lee , Allyn T. Londregan , Jana Polivkova , David A. Price , Qifang Li
IPC分类号： C07D401/04 , C07D405/14 , C07D401/14 , A61K31/506 , A61K45/06 , C07D409/14
摘要： Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
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公开(公告)号：US20180258081A1
公开(公告)日：2018-09-13
申请号：US15977238
申请日：2018-05-11
申请人： Pfizer Inc.
发明人： Markus Boehm , Shawn Cabral , Matthew S. Dowling , Kentaro Futatsugi , Kim Huard , Esther Cheng Yin Lee , Allyn T. Londregan , Jana Polivkova , David A. Price , Qifang Li
IPC分类号： C07D405/14 , C07D401/14 , C07D409/14 , A61K31/506 , A61K45/06
摘要： Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
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公开(公告)号：US11866425B2
公开(公告)日：2024-01-09
申请号：US17345064
申请日：2021-06-11
申请人： Pfizer Inc.
发明人： Markus Boehm , Shawn Cabral , Matthew S. Dowling , Kentaro Futatsugi , Kim Huard , Esther Cheng Yin Lee , Allyn T. Londregan , Jana Polivkova , David A. Price , Qifang Li
IPC分类号： A61K31/505 , A61P3/00 , A61P3/10 , A61P3/06 , C07D405/14 , C07D401/14 , A61K31/506 , A61K45/06 , C07D409/14
CPC分类号： C07D405/14 , A61K31/506 , A61K45/06 , C07D401/14 , C07D409/14 , A61P3/00 , A61P3/06 , A61P3/10 , C07B2200/13
摘要： Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
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公开(公告)号：US20210309646A1
公开(公告)日：2021-10-07
申请号：US17345064
申请日：2021-06-11
申请人： Pfizer Inc.
发明人： Markus Boehm , Shawn Cabral , Matthew S. Dowling , Kentaro Futatsugi , Kim Huard , Esther Cheng Yin Lee , Allyn T. Londregan , Jana Polivkova , David A. Price , Qifang Li
IPC分类号： C07D405/14 , C07D401/14 , A61K31/506 , A61K45/06 , C07D409/14
摘要： Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
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公开(公告)号：US20200181127A1
公开(公告)日：2020-06-11
申请号：US16793441
申请日：2020-02-18
申请人： Pfizer Inc.
发明人： Markus Boehm , Shawn Cabral , Matthew S. Dowling , Kentaro Futatsugi , Kim Huard , Esther Cheng Yin Lee , Allyn T. Londregan , Jana Polivkova , David A. Price , Qifang Li
IPC分类号： C07D405/14 , C07D409/14 , A61K45/06 , A61K31/506 , C07D401/14
摘要： Compounds of Formula I that inhibit the activity of the diacylglycerol acyltransferase 2 (DGAT2) and their uses in the treatment of diseases linked thereto in animals are described herein.
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