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公开(公告)号:US20230201283A1
公开(公告)日:2023-06-29
申请号:US17790160
申请日:2021-01-05
申请人: Pfizer Inc.
发明人: Joseph John Binder , Michael Dale Eisenbraun , Douglas Hanahan , David H. Kirn , Clare Lees , Prajit Limsirichai , Liliana Maruri Avidal
IPC分类号: A61K35/768 , C12N15/86 , A61K39/395 , C07K14/55 , C12N9/12 , A61P35/00
CPC分类号: A61K35/768 , A61K39/3955 , A61P35/00 , C07K14/55 , C12N9/1211 , C12N15/86 , C12Y207/01021 , C12N2710/24132 , C12N2710/24143
摘要: The present disclosure provides a replication-competent, recombinant oncolytic vaccinia virus (RVV), compositions comprising the RVV, and use of the RVV or composition for inducing oncolysis in an individual having a tumor.